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Chemical Compound Review:

Ferric oxalate ethanedioate; iron(+3) cation; hydrate

Synonyms: AC1LANCY, 381446_ALDRICH, iron(3+); oxalate; hydrate, Iron(III) oxalate hexahydrate

This record was replaced with 971.

Gillam, D.G. et al., Gillam, D.G. et al., Dragolich, W.E. et al., Wang, H.L. et al., Ng, L.P. et al., et al.

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Disease relevance of oxalic acid

The aim of this study was to evaluate the effectiveness of a 6% ferric oxalate solution applied during periodontal surgery to prevent post-operative tooth hypersensitivity [1].

High impact information on oxalic acid

Thus, relative to the number of crystals that form, no chemical pretreatment of radicular dentin is indicated prior to application of ferric oxalate in the treatment of root sensitivity [2].
Effects of purified ferric oxalate/nitric acid solutions as a pretreatment for the NTG-GMA and PMDM bonding system [3].

Chemical compound and disease context of oxalic acid

The aim of this randomized double-blind, split mouth 4-week clinical study, therefore was to determine whether a 1-min application of ferric oxalate (Sensodyne Sealant) on exposed root dentine was effective in reducing dentine hypersensitivity (DH) [4].

Associations of oxalic acid with other chemical compounds

Of all the agents tested, ferric oxalate, the active ingredient of Sensodyne Sealant, produced crystal-like structures which occluded a higher proportion of the tubules across the dentine disc surface [5].
The effects of phosphoric acid, sodium hypochlorite, ferric oxalate and Scotchbond Multipurpose on the rate of pressure change across dentine: a laboratory study [6].

Analytical, diagnostic and therapeutic context of oxalic acid

The morphological changes produced, in vitro, by application of ferric oxalate on enamel surfaces were examined by scanning electron microscopy [7].

References

Evaluation of ferric oxalate as an agent for use during surgery to prevent post-operative root hypersensitivity. Wang, H.L., Yeh, C.T., Smith, F., Burgett, F.G., Richards, P., Shyr, Y., O'Neal, R. J. Periodontol. (1993) [Pubmed]
An in vitro study of dentinal tubule occlusion by ferric oxalate. Dragolich, W.E., Pashley, D.H., Brennan, W.A., O'Neal, R.B., Horner, J.A., Van Dyke, T.E. J. Periodontol. (1993) [Pubmed]
Effects of purified ferric oxalate/nitric acid solutions as a pretreatment for the NTG-GMA and PMDM bonding system. Blosser, R.L., Bowen, R.L. Dental materials : official publication of the Academy of Dental Materials. (1988) [Pubmed]
Clinical evaluation of ferric oxalate in relieving dentine hypersensitivity. Gillam, D.G., Newman, H.N., Davies, E.H., Bulman, J.S., Troullos, E.S., Curro, F.A. Journal of oral rehabilitation. (2004) [Pubmed]
Scanning electron microscopy (SEM) investigation of selected desensitizing agents in the dentine disc model. Gillam, D.G., Khan, N., Mordan, N.J., Barber, P.M. Endodontics & dental traumatology. (1999) [Pubmed]
The effects of phosphoric acid, sodium hypochlorite, ferric oxalate and Scotchbond Multipurpose on the rate of pressure change across dentine: a laboratory study. Ng, L.P., Wilson, P.R. Journal of oral rehabilitation. (2005) [Pubmed]
Morphological effects produced, in vitro, by ferric oxalate treatment of enamel surfaces. A preliminary SEM study. Rodde, J. Bulletin du Groupement international pour la recherche scientifique en stomatologie & odontologie. (1992) [Pubmed]

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