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Chemical Compound Review:

Femodene (8R,9S,10R,13S,14R,17S)-13- ethyl-17...

Synonyms: Harmonet, Melodene, Femovan, Meliane, Minulet, ...

Deijen, J.B. et al., Fotherby, K. et al., Loudon, N.B. et al.

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High impact information on Minulet

No pregnancies were reported in either group, despite tablet-taking errors recorded in 6.3% of the Femodene group and 7.6% of the Microgynon-30 group [1].

Analytical, diagnostic and therapeutic context of Minulet

These minimal effects on metabolism, combined with its high efficacy and acceptability shown in clinical trials, makes Femodene an ideal alternative to currently used oral contraceptives [2].
The objective of the study was to evaluate the effect of Minulet, a new low-dose oral contraceptive on mood in two groups and to compare the effect with a control group of women not taking oral contraceptives (OC) [3].

References

A double-blind comparison of the efficacy and acceptability of Femodene and Microgynon-30. Loudon, N.B., Kirkman, R.J., Dewsbury, J.A. Eur. J. Obstet. Gynecol. Reprod. Biol. (1990) [Pubmed]
Metabolic investigations with Femodene--an oral contraceptive containing gestodene and ethinyloestradiol. Fotherby, K., Trayner, I., Longthorne, P.N., Lee, B., Watson, H.R. Contraception. (1987) [Pubmed]
Use of a monophasic, low-dose oral contraceptive in relation to mental functioning. Deijen, J.B., Duyn, K.J., Jansen, W.A., Klitsie, J.W. Contraception. (1992) [Pubmed]

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