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Chemical Compound Review

guanosine     2-amino-9-[(2R,3R,4S,5R)-3,4- dihydroxy-5...

Synonyms: Guanosin, Guanozin, vernine, Ribonucleoside, PubChem9300, ...
 
 
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High impact information on guanosine

  • This base pair is part of a self-consistent experimental system based on lipophilic ribose derivatives of cytidine (C), guanosine (G) and O6-methylguanosine (O6MeG) that are soluble in non-aqueous, low dielectric solvents at appreciable concentrations [1].
 

Analytical, diagnostic and therapeutic context of guanosine

  • On the basis of circular dichroism, proton magnetic resonance, and S(1) nuclease digestion data, it seemed that 2-FA-induced damage to DNA was less than that induced by 2-FAA modification of G at the C-8 position [2].

References

  1. Variable temperature infrared spectroscopy of cytosine-guanine base pairs: tautomerism versus polarization. MacPhail, R.A., Williams, L.D., Jones, D.A., Shaw, B.R. J. Biomol. Struct. Dyn. (1992) [Pubmed]
  2. N-2-fluorenylacetamide-induced conformational and functional damage to DNA. Grunberger, D. National Cancer Institute monograph. (1981) [Pubmed]
 
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