Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AG-C-27906 (3-hexadecanoyloxy-2-hydroxy- propyl)...

Synonyms: CHEMBL2074860, D1639_SIGMA, KST-1B4759, BBL010948, CTK1A2696, ...

Chen, X.S. et al., Nohara, K. et al., Deverre, J.R. et al.

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High impact information on AI3-03501

A new cerebroside, named typhonoside (1), was isolated from the root tuber of Typhonium giganteum Engl. along with three known compounds dipalmitin (2), alpha-monopalmitin (3) and 2,6-diamino-9-beta-D-ribofuranosylpurine (4) [1].
The esterification of melphalan by 1,3-dipalmitin allowed chemical stabilization of the alkylating agent in aqueous dispersion [2].
3. The same surfactant enriched with DPPC and dipalmitin, showing rapid spreading (1.8 s) and low minimal surface tension (6 mN/m) [3].

References

Chemical constituents of Typhonium giganteum Engl. Chen, X.S., Chen, D.H., Si, J.Y., Tu, G.Z. Journal of Asian natural products research. (2001) [Pubmed]
Synthesis of the orally macrofilaricidal and stable glycerolipidic prodrug of melphalan, 1,3-dipalmitoyl-2-(4'(bis(2''-chloroethyl)amino)phenylalaninoyl)gl ycerol. Deverre, J.R., Loiseau, P., Puisieux, F., Gayral, P., Letourneux, Y., Couvreur, P., Benoit, J.P. Arzneimittel-Forschung. (1992) [Pubmed]
Correlations between physical and physiological properties of various preparations of lung surfactant. Nohara, K., Berggren, P., Curstedt, T., Grossmann, G., Nilsson, R., Robertson, B. European journal of respiratory diseases. (1986) [Pubmed]

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