Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

COFFEE EXTRACT furan;1-methylpyridine-5- carboxylate;...

Synonyms: LS-2498, AC1OA83A, EINECS 283-481-1, Extract of coffee, Coffee bean extract, ...

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Coffee

The findings indicate that coffee intake may trigger myocardial infarction [1].
Coffee drinking has also been related to reduced risk of other liver diseases, thus suggesting a continuum of the favorable effect of coffee on liver function [2].
Coffee abstinence is associated with a lower hypertension risk than is low coffee consumption [3].

Associations of Coffee with other chemical compounds

After adjusting for age and sex, serum uric acid level associated with coffee intake of 4 to 5 and >/=6 cups daily was lower than that associated with no intake by 0.26 mg/dl (95% confidence interval [95% CI] 0.11, 0.41) and 0.43 mg/dl (95% CI 0.23, 0.65; P for trend < 0.001), respectively [4].
Common polymorphisms in genes involved in the metabolism of caffeine, catecholamines, homocysteine, and cholesterol can modulate the effect of coffee intake on cardiovascular parameters [5].

References

Transient exposure to coffee as a trigger of a first nonfatal myocardial infarction. Baylin, A., Hernandez-Diaz, S., Kabagambe, E.K., Siles, X., Campos, H. Epidemiology (2006) [Pubmed]
Coffee drinking and hepatocellular carcinoma risk: a meta-analysis. Bravi, F., Bosetti, C., Tavani, A., Bagnardi, V., Gallus, S., Negri, E., Franceschi, S., La Vecchia, C. Hepatology (2007) [Pubmed]
Coffee intake and incidence of hypertension. Uiterwaal, C.S., Verschuren, W.M., Bueno-de-Mesquita, H.B., Ocké, M., Geleijnse, J.M., Boshuizen, H.C., Peeters, P.H., Feskens, E.J., Grobbee, D.E. Am. J. Clin. Nutr. (2007) [Pubmed]
Coffee, tea, and caffeine consumption and serum uric acid level: the third national health and nutrition examination survey. Choi, H.K., Curhan, G. Arthritis Rheum. (2007) [Pubmed]
Acute and long-term cardiovascular effects of coffee: implications for coronary heart disease. Riksen, N.P., Rongen, G.A., Smits, P. Pharmacol. Ther. (2009) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share