Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

cis-zeatin (Z)-2-methyl-4-(7H-purin-6- ylamino)but-2...

Synonyms: AC1LEME2, CPD-4441, CHEBI:46570, Z0750_SIGMA, KST-1A3852, ...

Veach, Y.K. et al., Manzano, D. et al., Banowetz, G.M., Kasahara, H. et al., Martin, R.C. et al., et al.

Mok, Martin, Dobrev, Vanková, Ho, Yonekura-Sakakibara, Sakakibara, Mok,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on cis-zeatin

Based on the sequence of the gene ZOG1 encoding a trans-zeatin O-glucosyltransferase from Phaseolus (EC ), a cis-zeatin-specific O-glucosyltransferase was isolated from maize [1].
Because the prenylated adenine moiety of tRNA is usually of the cZ type, the formation of cZ in Arabidopsis seedlings might involve the transfer of DMAPP from the MVA pathway to tRNA [2].
The AHK4 receptor responded to trans-zeatin and m-topolin, while the ZmHK1 receptor responded also to cis-zeatin and o-topolin [3].
The existence of a maize (Zea mays) gene (cisZOG1) encoding an O-glucosyltransferase specific to cis-zeatin (R.C. Martin, M.C. Mok, J.E. Habben, D.W.S. Mok [2001] Proc Natl Acad Sci USA 98: 5922-5926) lends further support to this view [4].
The results are a clear indication that O-glucosylation of cis-zeatin is a natural metabolic process in maize [4].

Anatomical context of cis-zeatin

Overexpression of FPS in mitochondria also led to altered leaf cytokinin profile, with a reduction in the contents of physiologically active trans-zeatin- and isopentenyladenine-type cytokinins and their corresponding riboside monophosphates as well as enhanced levels of cis-zeatin 7-glucoside and storage cytokinin O-glucosides [5].

Associations of cis-zeatin with other chemical compounds

In particular, CRE1/AHK4 recognized at 1 microm concentration only trans-zeatin while AHK3 recognized cis-zeatin and dihydrozeatin as well, although with a lower sensitivity [6].
Three monoclonal antibodies (two IgG1 and one IgA) prepared against the plant cytokinin, cis-zeatin riboside, were characterized for use in a fluorescence competition enzyme linked immunosorbant assay (F-ELISA) [7].

References

A maize cytokinin gene encoding an O-glucosyltransferase specific to cis-zeatin. Martin, R.C., Mok, M.C., Habben, J.E., Mok, D.W. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
Distinct isoprenoid origins of cis- and trans-zeatin biosyntheses in Arabidopsis. Kasahara, H., Takei, K., Ueda, N., Hishiyama, S., Yamaya, T., Kamiya, Y., Yamaguchi, S., Sakakibara, H. J. Biol. Chem. (2004) [Pubmed]
Topolins and hydroxylated thidiazuron derivatives are substrates of cytokinin O-glucosyltransferase with position specificity related to receptor recognition. Mok, M.C., Martin, R.C., Dobrev, P.I., Vanková, R., Ho, P.S., Yonekura-Sakakibara, K., Sakakibara, H., Mok, D.W. Plant Physiol. (2005) [Pubmed]
O-glucosylation of cis-zeatin in maize. Characterization of genes, enzymes, and endogenous cytokinins. Veach, Y.K., Martin, R.C., Mok, D.W., Malbeck, J., Vankova, R., Mok, M.C. Plant Physiol. (2003) [Pubmed]
Overexpression of farnesyl diphosphate synthase in Arabidopsis mitochondria triggers light-dependent lesion formation and alters cytokinin homeostasis. Manzano, D., Busquets, A., Closa, M., Hoyerová, K., Schaller, H., Kamínek, M., Arró, M., Ferrer, A. Plant Mol. Biol. (2006) [Pubmed]
Two cytokinin receptors of Arabidopsis thaliana, CRE1/AHK4 and AHK3, differ in their ligand specificity in a bacterial assay. Spíchal, L., Rakova, N.Y., Riefler, M., Mizuno, T., Romanov, G.A., Strnad, M., Schmülling, T. Plant Cell Physiol. (2004) [Pubmed]
Monoclonal antibodies against the plant cytokinin, cis-zeatin riboside. Banowetz, G.M. Hybridoma (1993) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.