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Chemical Compound Review

Epiestriol     (8R,9S,13S,14S,16S,17S)-13- methyl-6,7,8,9...

Synonyms: Actriol, Epiestriolo, Epioestriol, Epiestriolum, Epioestriolum, ...
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Disease relevance of Epiestriol

  • The anti-inflammatory activity of 16-epiestriol was determined using a modified Winter's carrageenin rat paw edema model [1].

High impact information on Epiestriol


Chemical compound and disease context of Epiestriol


Associations of Epiestriol with other chemical compounds

  • Incubating spleen cells from untreated mice in concentrations of 16-epiestriol ranging from 1 mg/ml to 100 pg/ml did not alter profiles of IFN-gamma production, in contrast to the suppressive dose-response effects of hydrocortisone [2].


  1. 16-epiestriol: an anti-inflammatory steroid without glycogenic activity. Latman, N.S., Kishore, V., Bruot, B.C. Journal of pharmaceutical sciences. (1994) [Pubmed]
  2. 16-Epiestriol, a novel anti-inflammatory nonglycogenic steroid, does not inhibit IFN-gamma production by murine splenocytes. Miller, E., Bates, R., Bjorndahl, J., Allen, D., Burgio, D., Bouma, C., Stoll, J., Latman, N. J. Interferon Cytokine Res. (1998) [Pubmed]
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