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Chemical Compound Review

Vegadex     1-(2-chloroprop-2- enylsulfanyl)-N,N...

Synonyms: Vegedex, SULFALLATE, Thioallate, CDEC, Vegadex 20G, ...
 
 
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Disease relevance of Vegadex

  • 2-Chloroacrolein, the ultimate mutagen, formed on metabolism of the carcinogenc herbicides, diallate and sulfallate, and its 2-bromo-, 2,3-dichloro- and 2,3,3-trichloro- analogs are much more potent mutagens in the Ames Salmonella typhimurium strain TA1U0 assay than any other aldehydes examined previously or in this study [1].
 

High impact information on Vegadex

References

  1. Mutagenic potency of haloacroleins and related compounds. Rosen, J.D., Segall, Y., Casida, J.E. Mutat. Res. (1980) [Pubmed]
  2. Effects of metyrapone on microsomal-dependent Salmonella mutagenesis. Studies with chloroallyl ethers and model compounds. Distlerath, L.M., Loper, J.C., Tabor, M.W. Biochem. Pharmacol. (1983) [Pubmed]
  3. Metabolic activation of 3-(2-chloroethoxy)-1,2-dichloropropene: a mutagen structurally related to diallate, triallate, and sulfallate. Distlerath, L.M., Loper, J.C., Tabor, M.W. Environmental mutagenesis. (1985) [Pubmed]
 
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