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Chemical Compound Review:

Tridecanol tridecan-1-ol

Synonyms: n-Tridecanol, Tridecan-1-ol, ARONIS25149, CHEMBL24832, AGN-PC-00GU0S, ...

Tamura, K. et al., Alifimoff, J.K. et al., McKenzie, D. et al.

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High impact information on Tridecanol

2. IC50 concentrations were determined for the steady-state inhibition of the ACh-activated current by 31 general anaesthetics plus the non-anaesthetic alcohol n-tridecanol [1].
6. A cut-off in potency beyond dodecanol was established in experiments where tadpoles were maintained in supersaturated solutions of tridecanol for 20 h without demonstrable LRR [2].
The combined effects of high pressure (up to 300 bar) and a homologous series of 1-alkanols (ethanol C2 to 1-tridecanol C13) were studied on the main phase-transition temperature of dipalmitoylphosphatidylcholine (DPPC) vesicle membranes [3].

References

Actions of general anaesthetics on a neuronal nicotinic acetylcholine receptor in isolated identified neurones of Lymnaea stagnalis. McKenzie, D., Franks, N.P., Lieb, W.R. Br. J. Pharmacol. (1995) [Pubmed]
Anaesthetic potencies of primary alkanols: implications for the molecular dimensions of the anaesthetic site. Alifimoff, J.K., Firestone, L.L., Miller, K.W. Br. J. Pharmacol. (1989) [Pubmed]
High pressure antagonism of alcohol effects on the main phase-transition temperature of phospholipid membranes: biphasic response. Tamura, K., Kaminoh, Y., Kamaya, H., Ueda, I. Biochim. Biophys. Acta (1991) [Pubmed]

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