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Chemical Compound Review:

o-Toluate 2-methylbenzoic acid

Synonyms: O-TOLUIC ACID, SureCN4152, PubChem15431, Toluic acid, CHEMBL114957, ...

Liu, S.M. et al., Ghantous, H. et al., Higson, F.K. et al.

Liu, Chi,

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Disease relevance of o-Methylbenzoate

Degradation of 2-methylbenzoic acid by Pseudomonas cepacia MB2 [1].

High impact information on o-Methylbenzoate

Composition of the headspace gas affected the biotransformation pattern of toluic acid isomers in anoxic sediment slurries [2].
After xylene inhalation, on the other hand, methyl hippuric acid dominated over the non-conjugated metabolite, toluic acid [3].

References

Degradation of 2-methylbenzoic acid by Pseudomonas cepacia MB2. Higson, F.K., Focht, D.D. Appl. Environ. Microbiol. (1992) [Pubmed]
Effects of the headspace gas composition on anaerobic biotransformation of o-, m-, and p-toluic acid in sediment slurries. Liu, S.M., Chi, W.C. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering. (2003) [Pubmed]
Accumulation and turnover of metabolites of toluene and xylene in nasal mucosa and olfactory bulb in the mouse. Ghantous, H., Dencker, L., Gabrielsson, J., Danielsson, B.R., Bergman, K. Pharmacol. Toxicol. (1990) [Pubmed]

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