Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AGN-PC-00JEJX 10,13-dimethyl- 1,2,4,5,6,7,8,9,11,12,14,15...

Synonyms: AG-E-33109, AR-1H7285, FT-0619945, AC1L3C4Q, AC1Q6OU4, ...

Gennings, J.N. et al., Narendran, R. et al., Andresen, O.

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High impact information on Androst-16-en-3-one

Plasma concentrations of 5alpha-androst-16-en-3-one (5alpha-androstenone), the steroid responsible for boar taint, were measured by radioimmuno-assay in eight sows during the estrous cycle [1].
The presence of receptors to the "boar taint" pheromones 5alpha-androst-16-en-3-one and 5alpha-androst-16-en-3alpha-ol has been demonstrated in sow olfactory mucosa [2].
Studies on the receptors to 5alpha-androst-16-en-3-one and 5alpha-androst-16-en-3alpha-ol in sow nasal mucosa [2].
Analysis of receptor binding of 5alpha-androst-16-en-3-one gave a value for the affinity constant (Ka) of approx. 8.3-10(8) M-1 and the value for the molar concentration of binding sites (n[M]) was approx. 3.3 pmol/mg protein [2].
A radioimmunoassay for 5alpha-androst-16-en-3-one in porcine adipose tissue [3].

References

5alpha-Androstenone concentrations in sow plasma during the estrous cycle. Narendran, R., Etches, R.J., Hacker, R.R., Bowman, G.H. Theriogenology (1980) [Pubmed]
Studies on the receptors to 5alpha-androst-16-en-3-one and 5alpha-androst-16-en-3alpha-ol in sow nasal mucosa. Gennings, J.N., Gower, D.B., Bannister, L.H. Biochim. Biophys. Acta (1977) [Pubmed]
A radioimmunoassay for 5alpha-androst-16-en-3-one in porcine adipose tissue. Andresen, O. Acta Endocrinol. (1975) [Pubmed]

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