Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

Camphane 1,7,7- trimethylbicyclo[2.2.1]heptane

Synonyms: Bornane, Bornylane, Bornane (8CI), AG-F-59554, CHEBI:35783, ...

Van Roon, A. et al., Croteau, R. et al., Jung, C. et al.

Jung, Bec, Lange, Van Roon, Parsons, Govers,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Bornylane

The use of the molecular mechanics AMBER force field (FF) to predict product profiles for the hydroxylation of the monoterpenes 1R-camphor, 1S-camphor, 1R-norcamphor, 1S-norcamphor and camphane by the enzyme cytochrome P450cam from the soil bacterium Pseudomonas putida was investigated [1].

High impact information on Bornylane

In addition, subconformers have been found for the substrate-free and camphane-bound protein which show different CO binding kinetics [2].
Biosynthesis of monoterpenes: stereochemistry of the coupled isomerization and cyclization of geranyl pyrophosphate to camphane and isocamphane monoterpenes [3].

References

Cytochrome P450cam-monoterpene interactions. Van Roon, A., Parsons, J.R., Govers, H.A. SAR and QSAR in environmental research. (2005) [Pubmed]
Substrates modulate the rate-determining step for CO binding in cytochrome P450cam (CYP101). A high-pressure stopped-flow study. Jung, C., Bec, N., Lange, R. Eur. J. Biochem. (2002) [Pubmed]
Biosynthesis of monoterpenes: stereochemistry of the coupled isomerization and cyclization of geranyl pyrophosphate to camphane and isocamphane monoterpenes. Croteau, R., Gershenzon, J., Wheeler, C.J., Satterwhite, D.M. Arch. Biochem. Biophys. (1990) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share