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Chemical Compound Review

Camphane     1,7,7- trimethylbicyclo[2.2.1]heptane

Synonyms: Bornane, Bornylane, Bornane (8CI), AG-F-59554, CHEBI:35783, ...
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Disease relevance of Bornylane

  • The use of the molecular mechanics AMBER force field (FF) to predict product profiles for the hydroxylation of the monoterpenes 1R-camphor, 1S-camphor, 1R-norcamphor, 1S-norcamphor and camphane by the enzyme cytochrome P450cam from the soil bacterium Pseudomonas putida was investigated [1].

High impact information on Bornylane


  1. Cytochrome P450cam-monoterpene interactions. Van Roon, A., Parsons, J.R., Govers, H.A. SAR and QSAR in environmental research. (2005) [Pubmed]
  2. Substrates modulate the rate-determining step for CO binding in cytochrome P450cam (CYP101). A high-pressure stopped-flow study. Jung, C., Bec, N., Lange, R. Eur. J. Biochem. (2002) [Pubmed]
  3. Biosynthesis of monoterpenes: stereochemistry of the coupled isomerization and cyclization of geranyl pyrophosphate to camphane and isocamphane monoterpenes. Croteau, R., Gershenzon, J., Wheeler, C.J., Satterwhite, D.M. Arch. Biochem. Biophys. (1990) [Pubmed]
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