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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Blvra  -  biliverdin reductase A

Mus musculus

Synonyms: 0610006A11Rik, 2500001N03Rik, BVR A, Biliverdin reductase A, Biliverdin-IX alpha-reductase, ...
 
 
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High impact information on Blvra

  • Biliverdin reductase, Blvr, has been mapped on mouse chromosome 2, using an electrophoretic variant [1].
  • Localization of Blvr, biliverdin reductase, on mouse chromosome 2 [1].
  • In contrast to HO-1, the placental level of BVR-A activity remained low and did not show changes throughout the gestational period [2].
  • Here we describe the sequencing and annotation of a 341-kb region of mouse Chr 2 containing nine genes, including biliverdin reductase A (Blvra), and its comparison with the orthologous regions of the human and rat genomes [3].
 

Biological context of Blvra

  • In this study, we examined the distribution of HO-1 protein in the developing mouse embryo, as well as developmental changes of ho-1 gene expression, and the enzyme activity of HO and biliverdin IXalpha reductase (BVR-A) in placenta [2].

References

  1. Localization of Blvr, biliverdin reductase, on mouse chromosome 2. Peters, J., Ball, S.T., von Deimling, A. Genomics (1989) [Pubmed]
  2. Marked developmental changes in heme oxygenase-1 (HO-1) expression in the mouse placenta: correlation between HO-1 expression and placental development. Watanabe, S., Akagi, R., Mori, M., Tsuchiya, T., Sassa, S. Placenta (2004) [Pubmed]
  3. Comparative sequence analysis of a single-gene conserved segment in mouse and human. Thomas, J.W., Green, E.D. Mamm. Genome (2003) [Pubmed]
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