The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

Hba-ps4  -  hemoglobin alpha, pseudogene 4

Mus musculus

This record was replaced with 383229.
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Hba-ps4

  • Analysis of Hba-a4 alleles in CXB, BXH, and AKXL recombinant inbred strains placed Hba-a4 6.60 +/- 3.14 cM centromeric to H-2 [1].
  • We have now further characterized the second of these pseudogenes, Hba-a4 [1].
  • Hba-a4 is the first mammalian dispersed pseudogene to be localized in a linkage map, and should provide a useful marker for the region of chromosome 17 proximal to H-2 [1].
  • The usefulness of the library for chromosome walking was illustrated by constructing a 600-kilobase-long contig of DNA surrounding Hba-ps4, a DNA marker that is tightly linked to the fused (Fu) locus on chromosome 17 [2].
  • A parsimony analysis was performed on restriction sites at the Hba-ps4 pseudogene locus within one of four inversions associated with mouse t haplotypes [3].

Biological context of Hba-ps4


Anatomical context of Hba-ps4


Other interactions of Hba-ps4


Analytical, diagnostic and therapeutic context of Hba-ps4


  1. The alpha-globin pseudogene on mouse chromosome 17 is closely linked to H-2. D'Eustachio, P., Fein, B., Michaelson, J., Taylor, B.A. J. Exp. Med. (1984) [Pubmed]
  2. Genomic analysis using a yeast artificial chromosome library with mouse DNA inserts. Rossi, J.M., Burke, D.T., Leung, J.C., Koos, D.S., Chen, H., Tilghman, S.M. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  3. Phylogenetic analysis of the alpha-globin pseudogene-4 (Hba-ps4) locus in the house mouse species complex reveals a stepwise evolution of t haplotypes. Hammer, M.F., Silver, L.M. Mol. Biol. Evol. (1993) [Pubmed]
  4. Genomic rearrangement of the alpha-globin gene complex during mammalian evolution. Tan, H., Whitney, J.B. Biochem. Genet. (1993) [Pubmed]
  5. Comparative analysis of the alpha-like globin clusters in mouse, rat, and human chromosomes indicates a mechanism underlying breaks in conserved synteny. Tufarelli, C., Hardison, R., Miller, W., Hughes, J., Clark, K., Ventress, N., Frischauf, A.M., Higgs, D.R. Genome Res. (2004) [Pubmed]
  6. Human-mouse homologies in the region of the polycystic kidney disease gene (PKD1). Himmelbauer, H., Pohlschmidt, M., Snarey, A., Germino, G.G., Weinstat-Saslow, D., Somlo, S., Reeders, S.T., Frischauf, A.M. Genomics (1992) [Pubmed]
  7. Mapping of the Pim-1 oncogene in mouse t-haplotypes and its use to define the relative map positions of the tcl loci t0(t6) and tw12 and the marker tf (tufted). Ark, B., Gummere, G., Bennett, D., Artzt, K. Genomics (1991) [Pubmed]
  8. Genetic exchange across a paracentric inversion of the mouse t complex. Hammer, M.F., Bliss, S., Silver, L.M. Genetics (1991) [Pubmed]
WikiGenes - Universities