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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Nr2f2  -  nuclear receptor subfamily 2, group F,...

Rattus norvegicus

Synonyms: ARP-1, Apolipoprotein A-I regulatory protein 1, Arp1, COUP transcription factor 2, COUP transcription factor II, ...
 
 
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High impact information on Nr2f2

  • Matrix-mediated changes in the expression of HNF-4alpha isoforms and in DNA-binding activity of ARP-1 in primary cultures of rat hepatocytes [1].
  • Hepatocyte nuclear factor 4-mediated activation of rat CYP3A1 gene and its modes of modulation by apolipoprotein AI regulatory protein I and v-ErbA-related protein 3 [2].
  • Depletion of RS resulted in the complete disappearance of ARP-2 (13-14.5 kDa; pI 7.3-7.6), a decrease in abundance of ARP-7 and variable decreases in ARP-1 (approximately 9.5 kDa; pI 6.9-7.4) and ARP-6; ARP-1 and -2 are thought to be Sertoli cell-secreted proteins [3].
 

Analytical, diagnostic and therapeutic context of Nr2f2

  • In situ hybridization analysis showed that ARP-1, COUP-TF I, and TR4 were not expressed in magnocellular neurons at appreciable levels, but rather in surrounding structures [4].

References

  1. Matrix-mediated changes in the expression of HNF-4alpha isoforms and in DNA-binding activity of ARP-1 in primary cultures of rat hepatocytes. Runge, D., Runge, D.M., Daskalakis, N., Lubecki, K.A., Bowen, W.C., Michalopoulos, G.K. Biochem. Biophys. Res. Commun. (1999) [Pubmed]
  2. Hepatocyte nuclear factor 4-mediated activation of rat CYP3A1 gene and its modes of modulation by apolipoprotein AI regulatory protein I and v-ErbA-related protein 3. Ogino, M., Nagata, K., Miyata, M., Yamazoe, Y. Arch. Biochem. Biophys. (1999) [Pubmed]
  3. The role of specific germ cell types in modulation of the secretion of androgen-regulated proteins (ARPs) by stage VI-VIII seminiferous tubules from the adult rat. McKinnell, C., Sharpe, R.M. Mol. Cell. Endocrinol. (1992) [Pubmed]
  4. Expression of nuclear hormone receptors in the rat supraoptic nucleus. Lopes da Silva, S., Van Horssen, A.M., Chang, C., Burbach, J.P. Endocrinology (1995) [Pubmed]
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