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Gene Review

NR2F2  -  nuclear receptor subfamily 2, group F,...

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High impact information on NR2F2

  • Developmental regulation of the orphan receptor COUP-TF II gene in spinal motor neurons [1].
  • To begin to study the role of COUP-TFs during embryogenesis, we cloned a chicken COUP-TF (cCOUP-TF II) which is highly homologous to human COUP-TF II [1].
  • Here we show that repression of transactivation by these receptors is a general phenomenon for the COUP-TF subfamily, as inhibition is also observed with COUP-TF II [2].
  • COUP-TF II was enriched in mammalian amygdala including MeA and ExA to a lesser extent [3].


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