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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

NR2F2  -  nuclear receptor subfamily 2, group F,...

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High impact information on NR2F2

  • Developmental regulation of the orphan receptor COUP-TF II gene in spinal motor neurons [1].
  • To begin to study the role of COUP-TFs during embryogenesis, we cloned a chicken COUP-TF (cCOUP-TF II) which is highly homologous to human COUP-TF II [1].
  • Here we show that repression of transactivation by these receptors is a general phenomenon for the COUP-TF subfamily, as inhibition is also observed with COUP-TF II [2].
  • COUP-TF II was enriched in mammalian amygdala including MeA and ExA to a lesser extent [3].

References

  1. Developmental regulation of the orphan receptor COUP-TF II gene in spinal motor neurons. Lutz, B., Kuratani, S., Cooney, A.J., Wawersik, S., Tsai, S.Y., Eichele, G., Tsai, M.J. Development (1994) [Pubmed]
  2. Multiple mechanisms of chicken ovalbumin upstream promoter transcription factor-dependent repression of transactivation by the vitamin D, thyroid hormone, and retinoic acid receptors. Cooney, A.J., Leng, X., Tsai, S.Y., O'Malley, B.W., Tsai, M.J. J. Biol. Chem. (1993) [Pubmed]
  3. Subpallial amygdala and nucleus taeniae in birds resemble extended amygdala and medial amygdala in mammals in their expression of markers of regional identity. Yamamoto, K., Sun, Z., Wang, H.B., Reiner, A. Brain Res. Bull. (2005) [Pubmed]
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