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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Atp6v0b  -  ATPase, H+ transporting, lysosomal V0...

Mus musculus

Synonyms: 23 kDa subunit of V-ATPase, 2310024H13Rik, Atp6f, V-ATPase 21 kDa proteolipid subunit, V-type proton ATPase 21 kDa proteolipid subunit, ...
 
 
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High impact information on Atp6v0b

  • Despite this homology, however, the mouse cDNA does not complement the phenotype of a yeast strain in which the VMA16 gene has been disrupted [1].
  • Southern blot analysis indicated that the proteolipid is encoded by a single gene, Atp6f, in the mouse genome [2].
  • Atp6f was mapped to approximately 55 cM on chromosome 4, and its genomic organization is similar to that of the human gene: 8 exons separated by 7 introns, with boundaries matching the GT-AG rule [2].

References

  1. Expression and localization of the mouse homologue of the yeast V-ATPase 21-kDa Subunit c" (Vma16p). Nishi, T., Kawasaki-Nishi, S., Forgac, M. J. Biol. Chem. (2001) [Pubmed]
  2. Mouse Atp6f, the gene encoding the 23-kDa proteolipid of vacuolar proton translocating ATPase. Sun-Wada, G.H., Murakami, H., Nakai, H., Wada, Y., Futai, M. Gene (2001) [Pubmed]
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