Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

CGB2 - chorionic gonadotropin, beta polypeptide 2

Homo sapiens

Synonyms: Choriogonadotropin subunit beta variant 2

Hallast, P. et al., Rull, K. et al.

Rull, Laan,

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Disease relevance of CGB2

CGB1and CGB2 showed a considerable expression peak during the first trimester, both in normal and ectopic pregnancy, but not for RM [1].

High impact information on CGB2

The evolution and genomic landscape of CGB1 and CGB2 genes [2].

Biological context of CGB2

In silico prediction of putative transcription factor binding sites supports the hypothesis that CGB1 and CGB2 gene products are expressed in, and may contribute to, implantation and placental development [2].

Other interactions of CGB2

The function of two additional gene copies, CGB1 and CGB2, is still unknown [1].

References

Expression of beta-subunit of HCG genes during normal and failed pregnancy. Rull, K., Laan, M. Hum. Reprod. (2005) [Pubmed]
The evolution and genomic landscape of CGB1 and CGB2 genes. Hallast, P., Rull, K., Laan, M. Mol. Cell. Endocrinol. (2007) [Pubmed]

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