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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Ddx39b  -  DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B

Rattus norvegicus

Synonyms: 56 kDa U2AF65-associated protein, ATP-dependent RNA helicase p47, Bat1, Bat1a, DEAD box protein Uap56, ...
 
 
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High impact information on Bat1a

  • As RT1.L3 maps closely to the deletion in the mutant haplotype lm1, the RT1.L family can be located in the class I region extending from Bat1 to Pou5f1 [1].
  • Homology searches suggest a transition in the rat sequence with a proximal stretch containing Nfkbil1, ATP6G, and Bat1, which is homologous to the mouse H2-D region, and a more-distal stretch, which contains the class I gene and has many similarities to mouse H2-Q region sequences [2].
  • To determine whether the rat possesses an H2-D orthologue, we sequenced a cosmid clone that contains rat Bat1 and an adjacent class I gene, RT1.46 (l) [2].
  • The present study was undertaken to map these regions cytogenetically by several different approaches using cosmids specific for the Rps 18, Hspa1 and Bat1 genes [3].

References

  1. RT1.L: a family of MHC class Ib genes of the rat major histocompatibility complex with a distinct promoter structure. Lambracht-Washington, D., Düvel, H., Hänisch, L., Dinkel, A., Wonigeit, K. Immunogenetics (2004) [Pubmed]
  2. Does the rat have an H2-D orthologue next to Bat1? Lambracht-Washington, D., Fischer Lindahl, K. Immunogenetics (2002) [Pubmed]
  3. Cytogenetic localization of the growth and reproduction complex (Grc) in the rat and in the mouse and its position in relation to RT1.EC and other loci in the rat MHC. Helou, K., Yan, Q., Yuan, X.J., Kunz, H.W., Levan, G., Gill, T.J. Hereditas (1999) [Pubmed]
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