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Gene Review:

STK11IP - serine/threonine kinase 11 interacting...

Homo sapiens

Synonyms: KIAA1898, LIP1, LKB1-interacting protein 1, LKB1IP, STK11IP1, ...

Smith, D.P. et al., Srivastava, A. et al., Dicou, E.

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Disease relevance of STK11IP

LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1 [1].

High impact information on STK11IP

We have identified a novel leucine-rich repeat containing protein, LIP1, that interacts with LKB1 [1].
The LIP1 gene consists of 25 exons, maps to human chromosome 2q36 and encodes a protein of 121 kDa [1].
These results suggest a role for LIP1 and LIP2 in cell survival [2].
LIP1 was also compared with Lipozyme RM IM as biocatalysts [3].

References

LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1. Smith, D.P., Rayter, S.I., Niederlander, C., Spicer, J., Jones, C.M., Ashworth, A. Hum. Mol. Genet. (2001) [Pubmed]
Multiple biological activities for two peptides derived from the nerve growth factor precursor. Dicou, E. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
Candida rugosa lipase LIP1-catalyzed transesterification to produce human milk fat substitute. Srivastava, A., Akoh, C.C., Chang, S.W., Lee, G.C., Shaw, J.F. J. Agric. Food Chem. (2006) [Pubmed]

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STK11IP	Canis lupus familiaris
stk11ip	Danio rerio
STK11IP	Gallus gallus
STK11IP	Macaca mulatta
Stk11ip	Mus musculus
STK11IP	Pan troglodytes
Stk11ip	Rattus norvegicus
stk11ip	Xenopus (Silurana) tropicalis

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