Gene Review:
DDIT4L - DNA-damage-inducible transcript 4-like
Homo sapiens
Synonyms:
DNA damage-inducible transcript 4-like protein, HIF-1 responsive protein RTP801-like, Protein regulated in development and DNA damage response 2, REDD-2, REDD2, ...
- REDD2 gene is upregulated by modified LDL or hypoxia and mediates human macrophage cell death. Cuaz-Pérolin, C., Furman, C., Larigauderie, G., Legedz, L., Lasselin, C., Copin, C., Jaye, M., Searfoss, G., Yu, K.T., Duverger, N., Nègre-Salvayre, A., Fruchart, J.C., Rouis, M. Arterioscler. Thromb. Vasc. Biol. (2004)
- Dexamethasone Represses Signaling through the Mammalian Target of Rapamycin in Muscle Cells by Enhancing Expression of REDD1. Wang, H., Kubica, N., Ellisen, L.W., Jefferson, L.S., Kimball, S.R. J. Biol. Chem. (2006)