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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

ARHGAP33  -  Rho GTPase activating protein 33

Homo sapiens

Synonyms: FLJ39019, NOMA-GAP, Rho GTPase-activating protein 33, Rho-type GTPase-activating protein 33, SNX26, ...
 
 
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High impact information on SNX26

  • Overexpression of the full-length and C-terminal fragments of TCGAP inhibits insulin-stimulated glucose uptake and GLUT4 translocation [1].
  • TCGAP translocates to the plasma membrane in response to insulin in adipocytes [1].
 

Associations of SNX26 with chemical compounds

 

Regulatory relationships of SNX26

  • We show that NOMA-GAP promotes neurite outgrowth by tempering activation of the Cdc42/PAK signaling pathway in response to NGF [2].

References

  1. TCGAP, a multidomain Rho GTPase-activating protein involved in insulin-stimulated glucose transport. Chiang, S.H., Hwang, J., Legendre, M., Zhang, M., Kimura, A., Saltiel, A.R. EMBO J. (2003) [Pubmed]
  2. The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42. Rosário, M., Franke, R., Bednarski, C., Birchmeier, W. J. Cell Biol. (2007) [Pubmed]
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