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Gene Review:

RBP7 - retinol binding protein 7, cellular

Homo sapiens

Synonyms: CRABP-IV, CRABP4, CRBP4, CRBPIV, Cellular retinoic acid-binding protein 4, ...

Kwong, J. et al., Anantharaman, V. et al.

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High impact information on RBP7

Treatment with the DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine, resulted in reexpression of CRBP1 and CRBPIV gene expression in NPC cell lines [1].
Hypermethylation of CRBPI and CRBPIV CpG islands was found to be closely correlated with the loss of expression [1].
We predict that the interactions between FtsA and its functional partners in bacterial cell division are likely to be similar to the interactions of Rbp7p in the archaeo-eukaryotic RNA polymerase complex [2].

References

Epigenetic silencing of cellular retinol-binding proteins in nasopharyngeal carcinoma. Kwong, J., Lo, K.W., Chow, L.S., To, K.F., Choy, K.W., Chan, F.L., Mok, S.C., Huang, D.P. Neoplasia (2005) [Pubmed]
The SHS2 module is a common structural theme in functionally diverse protein groups, like Rpb7p, FtsA, GyrI, and MTH1598/TM1083 superfamilies. Anantharaman, V., Aravind, L. Proteins (2004) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

RBP7	Bos taurus
RBP7	Canis lupus familiaris
rbp7b	Danio rerio
RBP7	Gallus gallus
LOC722672	Macaca mulatta
Rbp7	Mus musculus
RBP7	Pan troglodytes
Rbp7	Rattus norvegicus

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