Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

He - Hemese

Drosophila melanogaster

Synonyms: CG31770, Dmel\CG31770, H2, he, hem

Kurucz, E. et al.

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High impact information on He

Hemese expression is restricted to the cell surfaces of hemocytes of all classes, and to the hematopoietic organs [1].
Hemese contains phosphotyrosine and the cytoplasmic region has potential phosphorylation sites, suggesting an involvement in signal transduction [1].
Depletion of Hemese by RNA interference has no obvious effect under normal conditions, but the cellular response to parasitic wasps is much enhanced [1].
We have identified a previously undescribed transmembrane protein, Hemese, from Drosophila melanogaster blood cells (hemocytes), by using a monoclonal pan-hemocyte antibody [1].

References

Hemese, a hemocyte-specific transmembrane protein, affects the cellular immune response in Drosophila. Kurucz, E., Zettervall, C.J., Sinka, R., Vilmos, P., Pivarcsi, A., Ekengren, S., Hegedüs, Z., Ando, I., Hultmark, D. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]

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