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Gene Review:

mocD - hypothetical protein

Agrobacterium tumefaciens

Baek, C.H. et al., Kim, K.S. et al.

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Disease relevance of mocD

Mutations in mocD and mocE, but not mocC, are suppressed by functions encoded by the chromosome or the 450-kb megaplasmid present in many Agrobacterium isolates [1].
To assess the level of dispersal of these two Amadori-utilizing systems, isolates of Agrobacterium spp. and related bacteria in the family Rhizobiaceae were examined by Southern analysis for homologs of socD and mocD [2].

High impact information on mocD

DNA sequence analysis revealed seven putative genes in this region: mocD (moc for mannityl opine catabolism) and mocE, oriented from right to left, and mocRCBAS, oriented from left to right [1].
The second, mocD dissimilates DFG formed in the pathway for catabolism of mannopine (MOP) a non-Amadori, imine-type member of the mannityl opine family characteristic of certain Ti and Ri plasmids [2].

References

Ti plasmid-encoded genes responsible for catabolism of the crown gall opine mannopine by Agrobacterium tumefaciens are homologs of the T-region genes responsible for synthesis of this opine by the plant tumor. Kim, K.S., Farrand, S.K. J. Bacteriol. (1996) [Pubmed]
Genes for utilization of deoxyfructosyl glutamine (DFG), an amadori compound, are widely dispersed in the family Rhizobiaceae. Baek, C.H., Farrand, S.K., Park, D.K., Lee, K.E., Hwang, W., Kim, K.S. FEMS Microbiol. Ecol. (2005) [Pubmed]

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