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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Cct7  -  chaperonin containing Tcp1, subunit 7 (eta)

Mus musculus

Synonyms: AA408524, AL022769, CCT-eta, Ccth, Cctz, ...
 
 
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High impact information on Cct7

  • Indeed, the Tetrahymena CCT eta and CCT gamma genes are up-regulated at 60-120 min of cilia recovery, and in conjugation when vegetative growth was resumed and cell division took place [1].
  • Southern blot indicated that the Ccth cDNA was located on the X chromosome, not deleted from the X* but closely linked to the deletion region [2].
  • Although the role of the Ccth containing region in sex determination of the wood lemming requires additional studies, the isolation of the mouse Ccth gene by the deletion Xp21-23 probe could be important since this gene is mainly expressed in testis [2].

References

  1. The Tetrahymena chaperonin subunit CCT eta gene is coexpressed with CCT gamma gene during cilia biogenesis and cell sexual reproduction. Cyrne, L., Guerreiro, P., Cardoso, A.C., Rodrigues-Pousada, C., Soares, H. FEBS Lett. (1996) [Pubmed]
  2. Characterization of the Xp21-23 region in the wood lemming, a region involved in XY sex reversal. Liu, W.S., Nordqvist, K., Lau, Y.F., Fredga, K. J. Exp. Zool. (2001) [Pubmed]
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