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Gene Review:

argT - lysine/arginine/ornithine ABC transporter...

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Higgins, C.F. et al., Higgins, C.F. et al., Wu, S.Q. et al.

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Disease relevance of argT

We have determined the nucleotide sequences of the regulatory regions from two amino acid transport operons from Salmonella typhimurium: dhuA, which regulates the histidine transport operon, and argTr, which regulates argT, the gene encoding the lysine-arginine-ornithine-binding protein, LAO [1].

High impact information on argT

The hisJ and argT genes of Salmonella typhimurium encode two periplasmic binding proteins, J and LAO, which are involved in histidine and arginine transport, respectively, and which interact with a common membrane-bound component, the P protein [2].
Together, these results indicate that nasR gene expression does not require specific upstream NtrC-binding sequences, as previously noted for argT gene expression in Salmonella typhimurium (G. Schmitz, K. Nikaido, and G. F.-L. Ames, Mol. Gen. Genet. 215:107-117, 1988) [3].

References

Regulatory regions of two transport operons under nitrogen control: nucleotide sequences. Higgins, C.F., Ames, G.F. Proc. Natl. Acad. Sci. U.S.A. (1982) [Pubmed]
Two periplasmic transport proteins which interact with a common membrane receptor show extensive homology: complete nucleotide sequences. Higgins, C.F., Ames, G.F. Proc. Natl. Acad. Sci. U.S.A. (1981) [Pubmed]
General nitrogen regulation of nitrate assimilation regulatory gene nasR expression in Klebsiella oxytoca M5al. Wu, S.Q., Chai, W., Lin, J.T., Stewart, V. J. Bacteriol. (1999) [Pubmed]

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