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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

REG3G  -  regenerating islet-derived 3 gamma

Homo sapiens

Synonyms: LPPM429, PAP IB, PAP-1B, PAP1B, PAPIB, ...
 
 
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Disease relevance of REG3G

  • IL-6 responsive elements existed in the 5'-upstream region of the human REG III gene indicating that the human REG III gene might be induced during acute pancreatitis [1].
 

High impact information on REG3G

  • By studying human databases and Expressed Sequence Tags library, we identified a new member called PAP IB [2].
  • After cloning PAP IB, however, we found that it was expressed almost only in pancreas, unlike REG Ialpha, whose expression is ubiquitous [2].
  • PAP IB, a new member of the Reg gene family: cloning, expression, structural properties, and evolution by gene duplication [2].
 

Analytical, diagnostic and therapeutic context of REG3G

References

  1. Molecular cloning, expression and chromosomal localization of a novel human REG family gene, REG III. Nata, K., Liu, Y., Xu, L., Ikeda, T., Akiyama, T., Noguchi, N., Kawaguchi, S., Yamauchi, A., Takahashi, I., Shervani, N.J., Onogawa, T., Takasawa, S., Okamoto, H. Gene (2004) [Pubmed]
  2. PAP IB, a new member of the Reg gene family: cloning, expression, structural properties, and evolution by gene duplication. Laurine, E., Manival, X., Montgelard, C., Bideau, C., Bergé-Lefranc, J.L., Erard, M., Verdier, J.M. Biochim. Biophys. Acta (2005) [Pubmed]
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