Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

CRYGB - crystallin, gamma B

Homo sapiens

Synonyms: CRYG2, CTRCT39, Gamma-B-crystallin, Gamma-crystallin 1-2, Gamma-crystallin B

Graw, J., Rogaev, E.I. et al.

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High impact information on CRYGB

A tri-nucleotide microsatellite marker for gamma-crystallin B gene (CRYG1) was found to co-segregate with PCC and yielded a maximum lod score of 10.62 at (theta = 0) [1].
The Cat2nop mutation is characterised by a mutation in the third exon of Crygb leading to a truncated gamma B-crystallin and the termination of lens fibre cell differentiation [2].

References

Linkage of polymorphic congenital cataract to the gamma-crystallin gene locus on human chromosome 2q33-35. Rogaev, E.I., Rogaeva, E.A., Korovaitseva, G.I., Farrer, L.A., Petrin, A.N., Keryanov, S.A., Turaeva, S., Chumakov, I., St George-Hyslop, P., Ginter, E.K. Hum. Mol. Genet. (1996) [Pubmed]
Mouse models of congenital cataract. Graw, J. Eye (London, England) (1999) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

CRYGB	Bos taurus
CRYGB	Canis lupus familiaris
crygs3	Danio rerio
CRYGB	Macaca mulatta
Crygb	Mus musculus
CRYGB	Pan troglodytes
Crygb	Rattus norvegicus

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