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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

UL39  -  ribonucleotide reductase subunit 1

Bovine herpesvirus 1

 
 
 
 
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Disease relevance of UL39

  • We sequenced the region of the bovine herpesvirus type 1 (BHV-1) genome corresponding to map units 0.172-0.230 (7964 bp), representing the UL39, UL38, and UL37 homologues of herpes simplex virus which encode the large subunit of ribonucleotide reductase (RR) and components of the viral capsid and the tegument, respectively [1].
  • Sequence analysis of the UL39, UL38, and UL37 homologues of bovine herpesvirus 1 and expression studies of UL40 and UL39, the subunits of ribonucleotide reductase [1].
 

High impact information on UL39

  • We also compared the expression kinetics of the large (R1, UL39) versus the small (R2, UL40) RR subunits during the course of in vitro BHV-1 infection by Western blotting using specifically developed and calibrated antisera [1].
 

Analytical, diagnostic and therapeutic context of UL39

References

  1. Sequence analysis of the UL39, UL38, and UL37 homologues of bovine herpesvirus 1 and expression studies of UL40 and UL39, the subunits of ribonucleotide reductase. Simard, C., Langlois, I., Styger, D., Vogt, B., Vlcek, C., Chalifour, A., Trudel, M., Schwyzer, M. Virology (1995) [Pubmed]
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