Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

egt - EGT; AcMNPV orf15

Bombyx mori nucleopolyhedrovirus

Smith, I. et al., Mukawa, S. et al., Clarke, E.E. et al., Murphy, C.I. et al.

Smith, Goodale,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of egt

The ecdysteroid UDP-glucosyltransferase (egt) gene of Mamestra brassicae multinucleocapsid nucleopolyhedrovirus (MbMNPV) has been cloned and characterized [1].
Primer extension analysis suggested that the major egt 5' transcription terminus is located within a baculovirus late gene promoter motif (GTAAG), in contrast to the early gene promoter contexts determined by others for three NPV egt mRNA 5' ends [2].
Sequence and in vivo transcription of Lacanobia oleracea granulovirus egt [2].
Enhanced expression, secretion, and large-scale purification of recombinant HIV-1 gp120 in insect cell using the baculovirus egt and p67 signal peptides [3].

High impact information on egt

A Japanese isolate of Mamestra brassicae nucleopolyhedrovirus (MabrNPV) was identified phylogenetically as a group II nucleopolyhedrovirus (NPV) that is related closely to other NPVs isolated from Mamestra spp. based on nucleotide sequence data of its polh, egt and lef-3 genes [4].

Chemical compound and disease context of egt

Database searching revealed that part of a published DNA sequence from Cryptophlebia leucotreta granulovirus appears to encode the N-terminal region of EGT, and the relative genomic locations of the egt and granulin genes in that virus were compared with their positions in LoGV [2].

Biological context of egt

We have determined the nucleotide sequence and located the major in vivo transcript termini of the Lacanobia oleracea granulovirus (LoGV) egt gene [2].

References

Characterization of the ecdysteroid UDP-glucosyltransferase gene from Mamestra brassicae nucleopolyhedrovirus. Clarke, E.E., Tristem, M., Cory, J.S., O'Reilly, D.R. J. Gen. Virol. (1996) [Pubmed]
Sequence and in vivo transcription of Lacanobia oleracea granulovirus egt. Smith, I., Goodale, C. J. Gen. Virol. (1998) [Pubmed]
Enhanced expression, secretion, and large-scale purification of recombinant HIV-1 gp120 in insect cell using the baculovirus egt and p67 signal peptides. Murphy, C.I., McIntire, J.R., Davis, D.R., Hodgdon, H., Seals, J.R., Young, E. Protein Expr. Purif. (1993) [Pubmed]
In vivo characterization of a group II nucleopolyhedrovirus isolated from Mamestra brassicae (Lepidoptera: Noctuidae) in Japan. Mukawa, S., Goto, C. J. Gen. Virol. (2006) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.