Disease relevance of Granulovirus

• The current study found zinc associated with both granulosis virus nucleocapsids and granulin by atomic absorption analysis [1].
• The Trichoplusia ni granulovirus helicase is unable to support replication of Autographa californica multicapsid nucleopolyhedrovirus in cells and larvae of T. ni [2].
• After the co-infection of larvae of the lepidopteran Cryptophlebia leucotreta with the two baculoviruses C. leucotreta granulosis virus and Cydia pomonella granulosis virus (CIGV and CpGV, respectively), three CpGV mutants and one CIGV mutant carrying insertions of 0.9 to 4.7 kb have been isolated [3].

High impact information on Granulovirus

• Poly(A)+ RNA was isolated from Pieris rapae granulosis virus (PrGV)-infected P. rapae larvae at times early (40 h postinoculation) and late (88 h postinoculation) in larval infection [4].
• One of these, SeMNPV ORF17/18 (Se17/18) shares 55% amino acid similarity to ORF129 of Xestia c-nigrum granulovirus (XcGV) [5].
• Phylogenetic trees of the granulovirus genes egt, granulin, pk-1 and me53 were constructed using maximum parsimony and distance analyses [6].
• In the present study, a recombinant putative DNA helicase (rP137) of Trichoplusia ni granulovirus (TnGV) was purified from insect cells infected with a recombinant Autographa californica multicapsid nucleopolyhedrovirus that overproduced rP137 [7].
• Database searching revealed that part of a published DNA sequence from Cryptophlebia leucotreta granulovirus appears to encode the N-terminal region of EGT, and the relative genomic locations of the egt and granulin genes in that virus were compared with their positions in LoGV [8].

Chemical compound and disease context of Granulovirus

• Trichoplusia ni granulosis virus granulin: a phenol-soluble, phosphorylated protein [9].
• The effect of sucrose content of diets on susceptibility to granulosis virus disease in Pieris brassicae [10].
• The protective treatments were cold storage (10 degrees C), controlled atmosphere (5% O2) storage, and application of the Indianmeal moth granulosis virus, and were designed to prevent establishment of Indianmeal moth, Plodia interpunctella (Hübner) [11].
• Reactivity of amino groups, phenoxy groups of tyrosine residues and some other charged groups of Tricoplusia ni granulosis virus granulin, which had rigid subunit structure abundant in beta-configuration, was investigated [12].

Biological context of Granulovirus

• Comprehensive physical map of the Cydia pomonella granulovirus genome and sequence analysis of the granulin gene region [13].
• The nucleotide sequence of a 2.2 kb genome region of the baculovirus Cryptophlebia leucotreta granulosis virus (CIGV) encompassing the granulin gene and a second open reading frame, designated ORF909, was determined [14].
• Two overlapping restriction fragments containing the Pieris brassicae granulosis virus (GV) granulin gene were cloned into plasmids [15].
• An inhibitor of apoptosis (iap) gene homolog (Tn-iap) of the Trichoplusia ni granulovirus (TnGV) was cloned, sequenced and mapped on the genome of TnGV [16].

Gene context of Granulovirus

• Sequence comparison with the granulin genes of different granulosis viruses indicated a very close relationship between CIGV and CpGV of about 96% amino acid identity [14].
• Molecular characterization and phylogenetic analysis of the Harrisina brillians granulovirus granulin gene [17].
• Identification, characterization and phylogenic analysis of conserved genes within the odvp-6e/odv-e56 gene region of Choristoneura fumiferana granulovirus [18].
• We have identified the enhancin proteins in four species of granulovirus (GV) [19].
• DNA-independent ATPase activity of the Trichoplusia ni granulovirus DNA helicase [7].

Analytical, diagnostic and therapeutic context of Granulovirus

• The granulin gene region of Cryptophlebia leucotreta granulosis virus: sequence analysis and phylogenetic considerations [14].

References