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Gene Review: 

odr-4  -  Protein ODR-4

Caenorhabditis elegans

 
 
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High impact information on odr-4

  • Social feeding is probably due to the sensation of noxious chemicals by ASH and ADL neurons; it requires the genes ocr-2 and osm-9, which encode TRP-related transduction channels, and odr-4 and odr-8, which are required to localize sensory chemoreceptors to cilia [1].
  • Other sensory neurons may suppress social feeding, as social feeding in ocr-2 and odr-4 mutants is restored by mutations in osm-3, a gene required for the development of 26 ciliated sensory neurons [1].

References

  1. Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli. de Bono, M., Tobin, D.M., Davis, M.W., Avery, L., Bargmann, C.I. Nature (2002) [Pubmed]
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