The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Activities of Daily Living

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Activities of Daily Living


Psychiatry related information on Activities of Daily Living


High impact information on Activities of Daily Living

  • The tacrine group had a significantly smaller decline in the activities of daily living [10].
  • In both groups the disease progressed; there was no difference in disease severity, capacity for daily living activities, or total amounts of dopamine agonists eventually used [11].
  • Social feeding is probably due to the sensation of noxious chemicals by ASH and ADL neurons; it requires the genes ocr-2 and osm-9, which encode TRP-related transduction channels, and odr-4 and odr-8, which are required to localize sensory chemoreceptors to cilia [12].
  • PARTICIPANTS: Twenty-six young (mean [SE] age, 28 [2] years) and 22 older (mean [SE] age, 70 [1] years) men, who were healthy and independent based on activities of daily living, physical examinations, and screening tests [13].
  • We identified and cloned a new gene, qui-1, necessary for quinine and SDS avoidance. qui-1 codes for a novel protein with WD-40 domains and which is expressed in the avoidance sensory neurons ASH and ADL [14].

Chemical compound and disease context of Activities of Daily Living


Biological context of Activities of Daily Living

  • Preincubation of macrophage line RAW264 with lipopolysaccharide (LPS) or purified protein derivative from Mycobacteria (PPD) for 2 days resulted in an average of 76% or 86% increase, respectively, in ADL of RBC, although there was no stimulation in RBC phagocytosis or in nonspecific or antibody-dependent lysis of tumor targets [20].
  • Significant increases in joint angles (measured as components of joint range of motion after administration of sodium hyaluronate) were observed; activities of daily living also improved significantly (P < 0.05 to P < 0.001) [21].
  • In order to determine an aerobic diving limit (ADL) in emperor penguins (Aptenodytes forsteri), post-dive blood lactate concentrations were measured in penguins foraging at an isolated sea ice hole [22].
  • Many health benefits are associated with musculoskeletal fitness, such as reduced coronary risk factors, increased bone mineral density (reduced risk of osteoporosis), increased flexibility, improved glucose tolerance, and greater success in completion of activities of daily living (ADL) [23].
  • Increasing age, male gender, longer pre-operative delay, a higher American Society of Anesthesiology score, a lower Mental Test score, and a lower activities of daily living (Barthel) score were associated with increased risks of death [24].

Anatomical context of Activities of Daily Living

  • The results for Lawton's scale of instrumental activities of daily living were significantly better (indicating greater independence and capacity) when folate intake and serum or erythrocyte folate concentrations were adequate (i.e., folate intake no less than recommended, > or = 14 nmol/L serum folate or > or = 360 nmol/L erythrocyte folate) [25].
  • Incidence of adenosis-like lesions (ADL) in the vaginal epithelium and stratification of the uterine epithelium (UST) were determined in both offspring and neonatally exposed mice at 30 days of age [26].
  • In dives of durations greater than the ADL, the calculated end-of-dive air sac O2 fraction was <4% [27].
  • Twenty-eight (78%) of thirty-six tendons in the glyceryl trinitrate group were asymptomatic with activities of daily living at six months, compared with twenty (49%) of forty-one tendons in the placebo group (p = 0.001, chi-square analysis) [28].
  • As both sex pheromones have been identified in urine, plasma, sweat and saliva of men and (especially hirsute) women we hypothesize that AL and AN are synthesized from ADL via ADN peripherically in tissues rich in 5 alpha-reductase, i.e. skin, axillary sweat glands and probably also the salivary glands [29].

Associations of Activities of Daily Living with chemical compounds


Gene context of Activities of Daily Living

  • Control EGF + TGF-alpha (-/-) had poor bud outgrowth, especially in the ADL region [34].
  • BASFI scoring was not sufficient in the present form; however, it is one of the candidate functional indexes for evaluating ADL in postoperative patients with OPLL [35].
  • ADL subjects had higher levels of insulin (16.7 +/- 7.5 versus 11.6 +/- 5.9 microIU/mL, P=0.008), soluble TNF receptor superfamily 1B (sTNFRSF1B) (3.3 +/- 0.7 versus 2.7 +/- 0.5 ng/mL, P=0.005), and interleukin-6 (IL-6) (2.6 +/- 2.2 versus 1.3 +/- 1.8 pg/mL, P=0.006) as compared to those of the non-ADL subjects [36].
  • Reduced CRH levels in CSF were found in the patients who showed severe dementia and poor activities of daily living (ADL) [37].
  • Primary generalized dystonia (PGD) associated with the early-onset generalized dystonia gene (DYT1) can cause severe disability, compromising an individual's ability to perform activities of daily living [38].

Analytical, diagnostic and therapeutic context of Activities of Daily Living


  1. Effectiveness of team-managed home-based primary care: a randomized multicenter trial. Hughes, S.L., Weaver, F.M., Giobbie-Hurder, A., Manheim, L., Henderson, W., Kubal, J.D., Ulasevich, A., Cummings, J. JAMA (2000) [Pubmed]
  2. Silent myocardial ischemia. Mechanisms and rationale for therapy. Kowalchuk, G.J., Nesto, R.W. Am. J. Med. (1989) [Pubmed]
  3. Tolcapone in stable Parkinson's disease: efficacy and safety of long-term treatment. Tolcapone Stable Study Group. Waters, C.H., Kurth, M., Bailey, P., Shulman, L.M., LeWitt, P., Dorflinger, E., Deptula, D., Pedder, S. Neurology (1998) [Pubmed]
  4. Double-blind evaluation of subthalamic nucleus deep brain stimulation in advanced Parkinson's disease. Kumar, R., Lozano, A.M., Kim, Y.J., Hutchison, W.D., Sime, E., Halket, E., Lang, A.E. Neurology (1998) [Pubmed]
  5. Treating depression in Alzheimer disease: efficacy and safety of sertraline therapy, and the benefits of depression reduction: the DIADS. Lyketsos, C.G., DelCampo, L., Steinberg, M., Miles, Q., Steele, C.D., Munro, C., Baker, A.S., Sheppard, J.M., Frangakis, C., Brandt, J., Rabins, P.V. Arch. Gen. Psychiatry (2003) [Pubmed]
  6. Short-term cardiovascular effects of methylphenidate and adderall. Findling, R.L., Short, E.J., Manos, M.J. Journal of the American Academy of Child and Adolescent Psychiatry. (2001) [Pubmed]
  7. The course of depression in the elderly: a longitudinal community-based study in Australia. Henderson, A.S., Korten, A.E., Jacomb, P.A., Mackinnon, A.J., Jorm, A.F., Christensen, H., Rodgers, B. Psychological medicine. (1997) [Pubmed]
  8. Hormone replacement therapy in postmenopausal women with Alzheimer's disease: a randomized, prospective study. Yoon, B.K., Kim, D.K., Kang, Y., Kim, J.W., Shin, M.H., Na, D.L. Fertil. Steril. (2003) [Pubmed]
  9. Impact of Alzheimer's disease and rivastigmine treatment on activities of daily living over the course of mild to moderately severe disease. Potki, S.G., Anand, R., Hartman, R., Veach, J., Grossberg, G. Prog. Neuropsychopharmacol. Biol. Psychiatry (2002) [Pubmed]
  10. A double-blind, placebo-controlled multicenter study of tacrine for Alzheimer's disease. The Tacrine Collaborative Study Group. Davis, K.L., Thal, L.J., Gamzu, E.R., Davis, C.S., Woolson, R.F., Gracon, S.I., Drachman, D.A., Schneider, L.S., Whitehouse, P.J., Hoover, T.M. N. Engl. J. Med. (1992) [Pubmed]
  11. Reappraisal of temporary levodopa withdrawal ("drug holiday") in Parkinson's disease. Mayeux, R., Stern, Y., Mulvey, K., Cote, L. N. Engl. J. Med. (1985) [Pubmed]
  12. Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli. de Bono, M., Tobin, D.M., Davis, M.W., Avery, L., Bargmann, C.I. Nature (2002) [Pubmed]
  13. Basal muscle amino acid kinetics and protein synthesis in healthy young and older men. Volpi, E., Sheffield-Moore, M., Rasmussen, B.B., Wolfe, R.R. JAMA (2001) [Pubmed]
  14. Worms taste bitter: ASH neurons, QUI-1, GPA-3 and ODR-3 mediate quinine avoidance in Caenorhabditis elegans. Hilliard, M.A., Bergamasco, C., Arbucci, S., Plasterk, R.H., Bazzicalupo, P. EMBO J. (2004) [Pubmed]
  15. Efficacy, safety, and tolerance of the non-ergoline dopamine agonist pramipexole in the treatment of advanced Parkinson's disease: a double blind, placebo controlled, randomised, multicentre study. Pinter, M.M., Pogarell, O., Oertel, W.H. J. Neurol. Neurosurg. Psychiatr. (1999) [Pubmed]
  16. High activity and reduced neurotoxicity of bi-fractionated oxaliplatin plus 5-fluorouracil/leucovorin for elderly patients with advanced colorectal cancer. Mattioli, R., Massacesi, C., Recchia, F., Marcucci, F., Cappelletti, C., Imperatori, L., Pilone, A., Rocchi, M., Cesta, A., Laici, G., Bonsignori, M., Lippe, P. Ann. Oncol. (2005) [Pubmed]
  17. Specific functional effects of memantine treatment in patients with moderate to severe Alzheimer's disease. Doody, R., Wirth, Y., Schmitt, F., Möbius, H.J. Dementia and geriatric cognitive disorders. (2004) [Pubmed]
  18. The effects of pentoxifylline on oxygenation, diffusion of carbon monoxide, and exercise tolerance in patients with COPD. Sasse, S.A., Causing, L.A., Stansbury, D.W., Light, R.W. Chest (1995) [Pubmed]
  19. Claims data studies of sedative-hypnotics and hip fractures in older people: exploring residual confounding using survey information. Schneeweiss, S., Wang, P.S. Journal of the American Geriatrics Society. (2005) [Pubmed]
  20. Antibody-dependent killing of erythrocyte and tumor targets by macrophage-related cell lines: enhancement by PPD and LPS. Ralph, P., Nakoinz, I. J. Immunol. (1977) [Pubmed]
  21. Clinical evaluation of high-molecular-weight sodium hyaluronate for the treatment of patients with periarthritis of the shoulder. Itokazu, M., Matsunaga, T. Clinical therapeutics. (1995) [Pubmed]
  22. Post-dive blood lactate concentrations in emperor penguins, Aptenodytes forsteri. Ponganis, P.J., Kooyman, G.L., Starke, L.N., Kooyman, C.A., Kooyman, T.G. J. Exp. Biol. (1997) [Pubmed]
  23. Musculoskeletal fitness, health outcomes and quality of life. Kell, R.T., Bell, G., Quinney, A. Sports medicine (Auckland, N.Z.) (2001) [Pubmed]
  24. Predicting survival after treatment for fracture of the proximal femur and the effect of delays to surgery. Elliott, J., Beringer, T., Kee, F., Marsh, D., Willis, C., Stevenson, M. Journal of clinical epidemiology. (2003) [Pubmed]
  25. Functional and psychic deterioration in elderly people may be aggravated by folate deficiency. Ortega, R.M., Mañas, L.R., Andrés, P., Gaspar, M.J., Agudo, F.R., Jiménez, A., Pascual, T. J. Nutr. (1996) [Pubmed]
  26. Development of vaginal adenosis-like lesions and uterine epithelial stratification in mice exposed perinatally to diethylstilbestrol. Iguchi, T., Takase, M., Takasugi, N. Proc. Soc. Exp. Biol. Med. (1986) [Pubmed]
  27. Air sac PO2 and oxygen depletion during dives of emperor penguins. Knower Stockard, T., Heil, J., Meir, J.U., Sato, K., Ponganis, K.V., Ponganis, P.J. J. Exp. Biol. (2005) [Pubmed]
  28. Topical glyceryl trinitrate treatment of chronic noninsertional achilles tendinopathy. A randomized, double-blind, placebo-controlled trial. Paoloni, J.A., Appleyard, R.C., Nelson, J., Murrell, G.A. The Journal of bone and joint surgery. American volume. (2004) [Pubmed]
  29. 16-Ene-steroids in the human testis. Smals, A.G., Weusten, J.J. J. Steroid Biochem. Mol. Biol. (1991) [Pubmed]
  30. A responsive outcome for Parkinson's disease neuroprotection futility studies. Elm, J.J., Goetz, C.G., Ravina, B., Shannon, K., Wooten, G.F., Tanner, C.M., Palesch, Y.Y., Huang, P., Guimaraes, P., Kamp, C., Tilley, B.C., Kieburtz, K. Ann. Neurol. (2005) [Pubmed]
  31. Evidence for aerobic insufficiency in women with systemic Lupus erythematosus. Keyser, R.E., Rus, V., Cade, W.T., Kalappa, N., Flores, R.H., Handwerger, B.S. Arthritis Rheum. (2003) [Pubmed]
  32. Prognostic value of high plasma brain natriuretic peptide concentrations in very elderly persons. Ueda, R., Yokouchi, M., Suzuki, T., Otomo, E., Katagiri, T. Am. J. Med. (2003) [Pubmed]
  33. Nortriptyline versus fluoxetine in the treatment of depression and in short-term recovery after stroke: a placebo-controlled, double-blind study. Robinson, R.G., Schultz, S.K., Castillo, C., Kopel, T., Kosier, J.T., Newman, R.M., Curdue, K., Petracca, G., Starkstein, S.E. The American journal of psychiatry. (2000) [Pubmed]
  34. Lack of expression of EGF and TGF-alpha in the fetal mouse alters formation of prostatic epithelial buds and influences the response to TCDD. Abbott, B.D., Lin, T.M., Rasmussen, N.T., Albrecht, R.M., Schmid, J.E., Peterson, R.E. Toxicol. Sci. (2003) [Pubmed]
  35. Bath ankylosing spondylitis functional index (BASFI) evaluation of postoperative patients with OPLL. Mori, K., Hukuda, S., Katsuura, A., Saruhashi, Y., Matsusue, Y. Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association. (2004) [Pubmed]
  36. Elevated soluble tumor necrosis factor receptor levels in non-obese adults with the atherogenic dyslipoproteinemia. Rosenson, R.S., Tangney, C.C., Levine, D.M., Parker, T.S., Gordon, B.R. Atherosclerosis (2004) [Pubmed]
  37. Cerebrospinal fluid and plasma corticotropin-releasing hormone in senile dementia. Suemaru, S., Hashimoto, K., Ogasa, T., Hirasawa, R., Makino, S., Ota, Z., Kageyama, J., Suemaru, K. Life Sci. (1991) [Pubmed]
  38. Bilateral globus pallidus internus deep brain stimulation therapy for primary generalized dystonia. Padaliya, B.B., Davis, T.L., Newman, W.J., Konrad, P.E., Covington, C.D., Gill, C.E., Abramovitch, A.I., Charles, P.D. Tennessee medicine : journal of the Tennessee Medical Association. (2004) [Pubmed]
  39. Predicting future functional status for seriously ill hospitalized adults. The SUPPORT prognostic model. Wu, A.W., Damiano, A.M., Lynn, J., Alzola, C., Teno, J., Landefeld, C.S., Desbiens, N., Tsevat, J., Mayer-Oakes, A., Harrell, F.E., Knaus, W.A. Ann. Intern. Med. (1995) [Pubmed]
  40. Resistance exercise in men receiving androgen deprivation therapy for prostate cancer. Segal, R.J., Reid, R.D., Courneya, K.S., Malone, S.C., Parliament, M.B., Scott, C.G., Venner, P.M., Quinney, H.A., Jones, L.W., D'Angelo, M.E., Wells, G.A. J. Clin. Oncol. (2003) [Pubmed]
  41. Quantitative pain assessment for routine care of rheumatoid arthritis patients, using a pain scale based on activities of daily living and a visual analog pain scale. Callahan, L.F., Brooks, R.H., Summey, J.A., Pincus, T. Arthritis Rheum. (1987) [Pubmed]
  42. Reliability and validity of disability questions for US Census 2000. Andresen, E.M., Fitch, C.A., McLendon, P.M., Meyers, A.R. American journal of public health. (2000) [Pubmed]
  43. Functional status outcomes in rehabilitation. Implications for prospective payment. Harada, N., Sofaer, S., Kominski, G. Medical care. (1993) [Pubmed]
WikiGenes - Universities