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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

klp-7  -  Protein KLP-7

Caenorhabditis elegans

 
 
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High impact information on klp-7

  • We additionally found that, although the failure of first polar body extrusion observed in alpha-Aurora A-microinjected oocytes is likely mediated by Eg5, the impairment of the metaphase plate rotation does not involve this kinesin-like protein [1].
  • One intriguing hypothesis is that AIR-2 acts to localize the mitotic kinesin-like protein ZEN-4 (also known as CeMKLP1), which later functions in cytokinesis [2].

References

  1. Involvement of Aurora A kinase during meiosis I-II transition in Xenopus oocytes. Castro, A., Mandart, E., Lorca, T., Galas, S. J. Biol. Chem. (2003) [Pubmed]
  2. The aurora-related kinase AIR-2 recruits ZEN-4/CeMKLP1 to the mitotic spindle at metaphase and is required for cytokinesis. Severson, A.F., Hamill, D.R., Carter, J.C., Schumacher, J., Bowerman, B. Curr. Biol. (2000) [Pubmed]
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