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Gene Review

Polr2c  -  polymerase (RNA) II (DNA directed)...

Mus musculus

Synonyms: 33kDa, DNA-directed RNA polymerase II 33 kDa polypeptide, DNA-directed RNA polymerase II subunit C, DNA-directed RNA polymerase II subunit RPB3, RNA polymerase II subunit 3, ...
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Disease relevance of Polr2c


Analytical, diagnostic and therapeutic context of Polr2c

  • The factor identified had an apparent molecular weight (Mw) of over 100kDa on a Superdex 200 column for molecular sieving HPLC, but an apparent Mw of 33kDa on SDS-PAGE under non-reducing conditions [2].


  1. RNA polymerase II subunit 3 is retained in the cytoplasm by its interaction with HCR, the psoriasis vulgaris candidate gene product. Corbi, N., Bruno, T., De Angelis, R., Di Padova, M., Libri, V., Di Certo, M.G., Spinardi, L., Floridi, A., Fanciulli, M., Passananti, C. J. Cell. Sci. (2005) [Pubmed]
  2. Purification and identification of a BMP-like factor from bovine serum. Kodaira, K., Imada, M., Goto, M., Tomoyasu, A., Fukuda, T., Kamijo, R., Suda, T., Higashio, K., Katagiri, T. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
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