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Gene Review

Fuk  -  fucokinase

Mus musculus

Synonyms: 1110046B12Rik, AI303278, L-fucose kinase
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High impact information on Fuk


Biological context of Fuk


Associations of Fuk with chemical compounds

  • In the alternative biosynthetic pathway, in the salvage metabolism, L-fucokinase (Fuk) synthesizes L-fucose-1-phosphate from free fucose [4].
  • We report here the cloning and expression of murine L-fucokinase and GDP-L-fucose pyrophosphorylase [2].
  • There is not a good correlation between fucokinase activity and protein-bound fucose, suggesting some tissues are more active in synthesis of fucose than others [3].


  1. Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism. Roos, C., Kolmer, M., Mattila, P., Renkonen, R. J. Biol. Chem. (2002) [Pubmed]
  2. Cloning and expression of murine enzymes involved in the salvage pathway of GDP-L-fucose. Niittymäki, J., Mattila, P., Roos, C., Huopaniemi, L., Sjöblom, S., Renkonen, R. Eur. J. Biochem. (2004) [Pubmed]
  3. Tissue distribution of L-fucokinase in rodents. Miller, E.N., Rupp, A.L., Lindberg, M.K., Wiese, T.J. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. (2005) [Pubmed]
  4. Differential gene expression of GDP-L-fucose-synthesizing enzymes, GDP-fucose transporter and fucosyltransferase VII. Niittymäki, J., Mattila, P., Renkonen, R. APMIS (2006) [Pubmed]
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