Gene Review:
DAAM2 - dishevelled associated activator of...
Homo sapiens
Synonyms:
Disheveled-associated activator of morphogenesis 2, KIAA0381
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Disease relevance of DAAM2
- DAAM2 mRNA was expressed in fetal heart, adult hypothalamus, eye, spinal cord, lung, prostate, kidney, and also in glioblastoma, oligodendroglioma, melanoma, mammary adenocarcinoma and chondrosarcoma [1].
High impact information on DAAM2
- DAAM2 gene was linked to the MOCS1 gene on human chromosome 6p21.3 with an interval less than 1 kb [1].
- DAAM2 was a 1077-amino-acid protein with Formin-homology FH1 and FH2 domains, which showed 68.9% total-amino-acid identity with DAAM1 [1].
- Here, we identified and characterized DAAM2 gene by using bioinformatics [1].
- DAAM2 gene consists of 27 exons, and gives rise to four splicing variants due to alternative splicing of alternative promoter type as well as of cassette exon type [1].
- Nucleotide sequence of DAAM2 cDNA was determined in silico by adding nucleotide position 1-793 of FLJ34430 onto the 5'-end of KIAA0381 [1].
References
- Identification and characterization of human DAAM2 gene in silico. Katoh, M., Katoh, M. Int. J. Oncol. (2003) [Pubmed]
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