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Gene Review

DAAM2  -  dishevelled associated activator of...

Homo sapiens

Synonyms: Disheveled-associated activator of morphogenesis 2, KIAA0381
 
 
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Disease relevance of DAAM2

 

High impact information on DAAM2

  • DAAM2 gene was linked to the MOCS1 gene on human chromosome 6p21.3 with an interval less than 1 kb [1].
  • DAAM2 was a 1077-amino-acid protein with Formin-homology FH1 and FH2 domains, which showed 68.9% total-amino-acid identity with DAAM1 [1].
  • Here, we identified and characterized DAAM2 gene by using bioinformatics [1].
  • DAAM2 gene consists of 27 exons, and gives rise to four splicing variants due to alternative splicing of alternative promoter type as well as of cassette exon type [1].
  • Nucleotide sequence of DAAM2 cDNA was determined in silico by adding nucleotide position 1-793 of FLJ34430 onto the 5'-end of KIAA0381 [1].

References

  1. Identification and characterization of human DAAM2 gene in silico. Katoh, M., Katoh, M. Int. J. Oncol. (2003) [Pubmed]
 
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