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Disease relevance of Chondrosarcoma


High impact information on Chondrosarcoma


Chemical compound and disease context of Chondrosarcoma


Biological context of Chondrosarcoma


Anatomical context of Chondrosarcoma


Gene context of Chondrosarcoma


Analytical, diagnostic and therapeutic context of Chondrosarcoma


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  3. Constitutive hedgehog signaling in chondrosarcoma up-regulates tumor cell proliferation. Tiet, T.D., Hopyan, S., Nadesan, P., Gokgoz, N., Poon, R., Lin, A.C., Yan, T., Andrulis, I.L., Alman, B.A., Wunder, J.S. Am. J. Pathol. (2006) [Pubmed]
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  16. Hereditary multiple exostoses (EXT): mutational studies of familial EXT1 cases and EXT-associated malignancies. Hecht, J.T., Hogue, D., Wang, Y., Blanton, S.H., Wagner, M., Strong, L.C., Raskind, W., Hansen, M.F., Wells, D. Am. J. Hum. Genet. (1997) [Pubmed]
  17. Loss of heterozygosity in chondrosarcomas for markers linked to hereditary multiple exostoses loci on chromosomes 8 and 11. Raskind, W.H., Conrad, E.U., Chansky, H., Matsushita, M. Am. J. Hum. Genet. (1995) [Pubmed]
  18. MYC amplification and polysomy 8 in chondrosarcoma: array comparative genomic hybridization, fluorescent in situ hybridization, and association with outcome. Morrison, C., Radmacher, M., Mohammed, N., Suster, D., Auer, H., Jones, S., Riggenbach, J., Kelbick, N., Bos, G., Mayerson, J. J. Clin. Oncol. (2005) [Pubmed]
  19. Phosphorylation of chondroitin sulfate in proteoglycans from the swarm rat chondrosarcoma. Oegema, T.R., Kraft, E.L., Jourdian, G.W., Van Valen, T.R. J. Biol. Chem. (1984) [Pubmed]
  20. Immunofluorescence localization of fibronectin in chondrosarcoma cartilage matrix. Kimata, K., Foidart, J.M., Pennypacker, J.P., Kleinman, H.K., Martin, G.R., Hewitt, A.T. Cancer Res. (1982) [Pubmed]
  21. Ultrastructural characterization of embryonic chick cartilage proteoglycan core protein and the mapping of a monoclonal antibody epitope. Dennis, J.E., Carrino, D.A., Schwartz, N.B., Caplan, A.I. J. Biol. Chem. (1990) [Pubmed]
  22. Complexes of matrilin-1 and biglycan or decorin connect collagen VI microfibrils to both collagen II and aggrecan. Wiberg, C., Klatt, A.R., Wagener, R., Paulsson, M., Bateman, J.F., Heinegård, D., Mörgelin, M. J. Biol. Chem. (2003) [Pubmed]
  23. ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1. Gao, G., Plaas, A., Thompson, V.P., Jin, S., Zuo, F., Sandy, J.D. J. Biol. Chem. (2004) [Pubmed]
  24. Differential diagnosis of chordoma, chondroid, and ependymal tumors as aided by anti-intermediate filament antibodies. Miettinen, M., Lehto, V.P., Dahl, D., Virtanen, I. Am. J. Pathol. (1983) [Pubmed]
  25. ADAMTS-9 is synergistically induced by interleukin-1beta and tumor necrosis factor alpha in OUMS-27 chondrosarcoma cells and in human chondrocytes. Demircan, K., Hirohata, S., Nishida, K., Hatipoglu, O.F., Oohashi, T., Yonezawa, T., Apte, S.S., Ninomiya, Y. Arthritis Rheum. (2005) [Pubmed]
  26. A far upstream, cell type-specific enhancer of the mouse thrombospondin 3 gene is located within intron 6 of the adjacent metaxin gene. Collins, M., Rojnuckarin, P., Zhu, Y.H., Bornstein, P. J. Biol. Chem. (1998) [Pubmed]
  27. Human chondrosarcoma secretes vascular endothelial growth factor to induce tumor angiogenesis and stores basic fibroblast growth factor for regulation of its own growth. Furumatsu, T., Nishida, K., Kawai, A., Namba, M., Inoue, H., Ninomiya, Y. Int. J. Cancer (2002) [Pubmed]
  28. HDAC4 represses vascular endothelial growth factor expression in chondrosarcoma by modulating RUNX2 activity. Sun, X., Wei, L., Chen, Q., Terek, R.M. J. Biol. Chem. (2009) [Pubmed]
  29. Electron microscopy of native cartilage oligomeric matrix protein purified from the Swarm rat chondrosarcoma reveals a five-armed structure. Mörgelin, M., Heinegård, D., Engel, J., Paulsson, M. J. Biol. Chem. (1992) [Pubmed]
  30. Purification of an insulin-like growth factor II receptor from rat chondrosarcoma cells. August, G.P., Nissley, S.P., Kasuga, M., Lee, L., Greenstein, L., Rechler, M.M. J. Biol. Chem. (1983) [Pubmed]
  31. The effect of cycloheximide on synthesis of proteoglycans by cultured chondrocytes from the Swarm rat chondrosarcoma. Kimura, J.H., Caputo, C.B., Hascall, V.C. J. Biol. Chem. (1981) [Pubmed]
  32. Cartilage link proteins. Biochemical and immunochemical studies of isolation and heterogeneity. Poole, A.R., Reiner, A., Mort, J.S., Tang, L.H., Choi, H.U., Rosenberg, L.C., Caputo, C.B., Kimura, J.H., Hascall, V.C. J. Biol. Chem. (1984) [Pubmed]
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