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MKRN2  -  makorin ring finger protein 2

Homo sapiens

Synonyms: HSPC070, RING finger protein 62, RNF62
 
 
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High impact information on MKRN2

  • Interestingly, a new gene named as HSPC070 on 3p was found to share a sequence of 105bp in 3' UTR with RAF gene in reversed transcription orientation [1].
  • Phylogenetic conservation of the makorin-2 gene, encoding a multiple zinc-finger protein, antisense to the RAF1 proto-oncogene [2].
 

Anatomical context of MKRN2

 

Other interactions of MKRN2

  • The data presented here describe a conserved vertebrate MKRN2 gene that is closely associated with the RAF1 locus [2].

References

  1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. Zhang, Q.H., Ye, M., Wu, X.Y., Ren, S.X., Zhao, M., Zhao, C.J., Fu, G., Shen, Y., Fan, H.Y., Lu, G., Zhong, M., Xu, X.R., Han, Z.G., Zhang, J.W., Tao, J., Huang, Q.H., Zhou, J., Hu, G.X., Gu, J., Chen, S.J., Chen, Z. Genome Res. (2000) [Pubmed]
  2. Phylogenetic conservation of the makorin-2 gene, encoding a multiple zinc-finger protein, antisense to the RAF1 proto-oncogene. Gray, T.A., Azama, K., Whitmore, K., Min, A., Abe, S., Nicholls, R.D. Genomics (2001) [Pubmed]
 
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