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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Mst1  -  Macrophage stimulating 1 (hepatocyte...

Rattus norvegicus

 
 
 
 
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High impact information on Mst1

  • CONCLUSIONS: Our results suggest that Mst1 plays an important role in the induction of apoptosis of VSMCs, mediating the vascular remodeling process, and may be a potential therapeutic target for vascular proliferative diseases [1].
  • Adenovirus-mediated overexpression of wild-type Mst1 (AdMst1) in VSMCs increased apoptotic cells with activation of caspase 3 [1].
  • Mst1 is a ubiquitously expressed serine/threonine kinase known to be activated in response to a wide variety of nonphysiological apoptotic stimuli [1].
  • Mst1 was induced and activated in the balloon-injured rat carotid artery [1].

References

  1. Critical role of Mst1 in vascular remodeling after injury. Ono, H., Ichiki, T., Ohtsubo, H., Fukuyama, K., Imayama, I., Hashiguchi, Y., Sadoshima, J., Sunagawa, K. Arterioscler. Thromb. Vasc. Biol. (2005) [Pubmed]
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