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Gene Review

KCTD13  -  potassium channel tetramerization domain...

Homo sapiens

Synonyms: BACURD1, BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1, BTB/POZ domain-containing protein KCTD13, FKSG86, PDIP1, ...
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High impact information on KCTD13


Biological context of KCTD13

  • The rat PDIP1 is mapped to chromosome 1q36 cM region, spans approximately 18.7 kb, and is organized into six exons [4].
  • No potent intrinsic activation domain was identified in either PDIP1 isoforms in mammalian one-hybrid assays, and mutation of all LXXLL motifs did not affect enhancement of PPARgamma-mediated transactivation [2].


  1. A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigen. He, H., Tan, C.K., Downey, K.M., So, A.G. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  2. Isolation and characterization of a transcriptional cofactor and its novel isoform that bind the deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma. Tomaru, T., Satoh, T., Yoshino, S., Ishizuka, T., Hashimoto, K., Monden, T., Yamada, M., Mori, M. Endocrinology (2006) [Pubmed]
  3. Regulation of mitochondrial morphology and cell survival by Mitogenin I and mitochondrial single-stranded DNA binding protein. Arakaki, N., Nishihama, T., Kohda, A., Owaki, H., Kuramoto, Y., Abe, R., Kita, T., Suenaga, M., Himeda, T., Kuwajima, M., Shibata, H., Higuti, T. Biochim. Biophys. Acta (2006) [Pubmed]
  4. Cloning of two rat PDIP1 related genes and their interactions with proliferating cell nuclear antigen. Zhou, J., Hu, X., Xiong, X., Liu, X., Liu, Y., Ren, K., Jiang, T., Hu, X., Zhang, J. J. Exp. Zoolog. Part A Comp. Exp. Biol. (2005) [Pubmed]
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