Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

rad17 - RFC related checkpoint protein Rad17

Schizosaccharomyces pombe 972h-

Sasaki, H. et al., Enoch, T. et al., Belenguer, P. et al.

Sasaki, Chen, Auclair, Moriyama, Kaji, Fukai, Kiriyama, Yamakawa, Fujii,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of rad17

We used palindromic PCR-driven cDNA differential display technique to identify and isolate a gene, human homologue of the Schizosaccharomyces pombe checkpoint gene rad17, from colon cancer tissues [1].

High impact information on rad17

The mutants define eight linkage groups, three of which consist of alleles of the rad1, rad3, and rad17 genes [2].
DNA repair mutants rad9 and rad17 did not arrest and were hypersensitive to phleomycin [3].

References

Overexpression of Hrad17 gene in non-small cell lung cancers correlated with lymph node metastasis. Sasaki, H., Chen, L.B., Auclair, D., Moriyama, S., Kaji, M., Fukai, I., Kiriyama, M., Yamakawa, Y., Fujii, Y. Lung Cancer (2001) [Pubmed]
Fission yeast genes involved in coupling mitosis to completion of DNA replication. Enoch, T., Carr, A.M., Nurse, P. Genes Dev. (1992) [Pubmed]
Effects of phleomycin-induced DNA damage on the fission yeast Schizosaccharomyces pombe cell cycle. Belenguer, P., Oustrin, M.L., Tiraby, G., Ducommun, B. Yeast (1995) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg