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Gene Review:

SNORD55 - small nucleolar RNA, C/D box 55

Homo sapiens

Synonyms: RNU39, RNU55, SNORD39, U39, U55

Singh, S.K. et al., Alam, S. et al., Kumon, Y. et al., Tovar, A.R. et al., van Hal, N.L. et al.

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High impact information on SNORD55

We also demonstrate for the first time that methylation of two nucleotides guided by a single box C/D RNA is sequential, that is, box C'/D' RNP-guided U39 methylation first requires box C/D RNP-guided methylation of C34 [1].
Alanine plasma concentrations were significantly higher with the U55 diet at 1900 and significantly lower with the R55 diet at 0930 with respect to the other diets [2].
Previous functional studies revealed that the minimal hairpin ribozyme exhibited "gain-of-function" cleavage properties resulting from U39C or U39 to propyl linker (C3) modifications [3].
Immuno-histochemistry was performed with 3 different anti-v6 antibodies (U36, U39 and VFF18) on a large panel of HNSCC cell lines and tumors [4].
In the plasmid constructs of U39 (PON1 upstream -1232/-6), U682 (-589/-6), U797 (-472/-6) and U953 (-318/-6), U953 showed a stepwise upregulation in basal promoter activity [5].

References

Sequential 2'-O-methylation of archaeal pre-tRNATrp nucleotides is guided by the intron-encoded but trans-acting box C/D ribonucleoprotein of pre-tRNA. Singh, S.K., Gurha, P., Tran, E.J., Maxwell, E.S., Gupta, R. J. Biol. Chem. (2004) [Pubmed]
Neutral and basic amino acid concentrations in plasma during the day in subjects fed with two model rural and two model urban Mexican diets. Tovar, A.R., Ascencio, C., Torres, N., Gómez, E., Bourges, H. Am. J. Clin. Nutr. (1996) [Pubmed]
Conformational heterogeneity at position U37 of an all-RNA hairpin ribozyme with implications for metal binding and the catalytic structure of the S-turn. Alam, S., Grum-Tokars, V., Krucinska, J., Kundracik, M.L., Wedekind, J.E. Biochemistry (2005) [Pubmed]
Characterization of CD44v6 isoforms in head-and-neck squamous-cell carcinoma. van Hal, N.L., van Dongen, G.A., Stigter-van Walsum, M., Snow, G.B., Brakenhoff, R.H. Int. J. Cancer (1999) [Pubmed]
Human paraoxonase-1 gene expression by HepG2 cells is downregulated by interleukin-1beta and tumor necrosis factor-alpha, but is upregulated by interleukin-6. Kumon, Y., Suehiro, T., Ikeda, Y., Hashimoto, K. Life Sci. (2003) [Pubmed]

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