Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

OXGR1 - oxoglutarate (alpha-ketoglutarate) receptor 1

Homo sapiens

Synonyms: 2-oxoglutarate receptor 1, Alpha-ketoglutarate receptor 1, G-protein coupled receptor 80, G-protein coupled receptor 99, GPR80, ...

Wittenberger, T. et al., He, W. et al.

Wittenberger, Hellebrand, Munck, Kreienkamp, Schaller, Hampe,

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High impact information on OXGR1

We also report that GPR99 (ref. 4), a close relative of GPR91, responds to alpha-ketoglutarate, another intermediate in the citric acid cycle [1].
GPR99, a new G protein-coupled receptor with homology to a new subgroup of nucleotide receptors [2].
CONCLUSIONS: We identified a new orphan receptor, GPR99, with homology to the family of G protein-coupled nucleotide receptors [2].

References

Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors. He, W., Miao, F.J., Lin, D.C., Schwandner, R.T., Wang, Z., Gao, J., Chen, J.L., Tian, H., Ling, L. Nature (2004) [Pubmed]
GPR99, a new G protein-coupled receptor with homology to a new subgroup of nucleotide receptors. Wittenberger, T., Hellebrand, S., Munck, A., Kreienkamp, H.J., Schaller, H.C., Hampe, W. BMC Genomics (2002) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

OXGR1	Bos taurus
OXGR1	Canis lupus familiaris
LOC569401	Danio rerio
oxgr1a.3	Danio rerio
oxgr1a.2	Danio rerio
oxgr1a.1	Danio rerio
OXGR1	Gallus gallus
OXGR1	Macaca mulatta
Oxgr1	Mus musculus
OXGR1	Pan troglodytes
Oxgr1	Rattus norvegicus

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