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Gene Review:

SI - sucrase-isomaltase

Bos taurus

This record was replaced with 504366.

Núñez-Dominguez, R. et al., Larcher, V.F. et al., Takahama, K., Gambacurta, A. et al., Peterson, M.D. et al.

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Disease relevance of SI

Other diagnoses included primary sucrase-isomaltase deficiency, Shwachman's syndrome, ulcerative colitis, ganglioneuroma, defective opsonization, staphylococcal pneumonia, and Hirschsprung's disease [1].

High impact information on SI

Sucrase-isomaltase was not reliably detectable until 9 d by immunofluorescence, after brush border assembly was complete [2].
The sandwich enzyme immunoassays for specific antigens to the liver (LSA), the small intestine (sucrase-isomaltase), and the heart (cardiac troponin I) were developed [3].
Records of 328 Angus, Hereford, Shorthorn, and first-cross cows produced from 1960 to 1963 were used to estimate heterosis (h) and individual (gI) and maternal (gM) average breed effects on cumulative survival (CS) by ages to 12 yr, longevity (L), and size (SI) and condition of incisors at 10 to 15 yr of age [4].
SI mRNA possesses a 90-nt 5'-end region, absent in BPTI mRNA, with an additional 5' AUG in a different open reading frame (ORF) [5].

References

Protracted diarrhoea in infancy. Analysis of 82 cases with particular reference to diagnosis and management. Larcher, V.F., Shepherd, R., Francis, D.E., Harries, J.T. Arch. Dis. Child. (1977) [Pubmed]
An in vitro model for the analysis of intestinal brush border assembly. II. Changes in expression and localization of brush border proteins during cell contact-induced brush border assembly in Caco-2BBe cells. Peterson, M.D., Bement, W.M., Mooseker, M.S. J. Cell. Sci. (1993) [Pubmed]
Forensic application of organ-specific antigens. Takahama, K. Forensic Sci. Int. (1996) [Pubmed]
Heterosis for survival and dentition in Hereford, Angus, Shorthorn, and crossbred cows. Núñez-Dominguez, R., Cundiff, L.V., Dickerson, G.E., Gregory, K.E., Koch, R.M. J. Anim. Sci. (1991) [Pubmed]
Differential in vitro translation of the precursors of bovine pancreatic trypsin inhibitor and its isoinhibitor II is controlled by the 5'-end region of their mRNAs. Gambacurta, A., Piro, M.C., Ascoli, F. Biochim. Biophys. Acta (1993) [Pubmed]

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