The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • SNPedia

Table of contents

About

Terms

 

Gene Review: 

TPI1  -  triosephosphate isomerase 1

Bos taurus

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on TPI1

  • Flow cytometric analysis of DNA content and synthesis in BASMCs treated with TPI-1 or calpeptin additionally revealed the presence of a distinct cell cycle block in the G2-M compartment [1].
  • By Northern analysis of mRNA after serum addition, TPI-1 caused a fourfold decrease in the transient elevation of fos and myc proto-oncogene as well as a decrease in the levels of both muscle and nonmuscle actin mRNA induced early after serum addition [1].
  • The kinetics of the reverse reaction were studied by coupling the phosphatase reaction to the aldolase, triosephosphate isomerase, and glycerolphosphate dehydrogenase reactions [2].
  • The strong inhibition of triosephosphate isomerase by the natural beta-carbolines may explain their neurotoxic actions [3].
  • The location of the triose phosphate isomerase (TPI1) gene and one of the nucleolar organizer regions (RNR) on sheep 3q was confirmed by Southern analysis [4].
 

Biological context of TPI1

  • The cell cycle progression block was gradually lost as the delay from serum to TPI-1 application was increased from 6 to 12 hours [1].
 

Anatomical context of TPI1

References

  1. Effects of thiol protease inhibitors on cell cycle and proliferation of vascular smooth muscle cells in culture. March, K.L., Wilensky, R.L., Roeske, R.W., Hathaway, D.R. Circ. Res. (1993) [Pubmed]
  2. Kinetic studies of bovine liver fructose-1,6-bisphosphatase. Casazza, J.P., Stone, S.R., Fromm, H.J. J. Biol. Chem. (1979) [Pubmed]
  3. The strong inhibition of triosephosphate isomerase by the natural beta-carbolines may explain their neurotoxic actions. Bonnet, R., Pavlovic, S., Lehmann, J., Rommelspacher, H. Neuroscience (2004) [Pubmed]
  4. Mapping of MYF5, C1R, MYHL, TPI1, IAPP, A2MR and RNR onto sheep chromosome 3q. Broad, T.E., Burkin, D.J., Jones, C., Lewis, P.E., Ansari, H.A., Pearce, P.D. Anim. Genet. (1993) [Pubmed]
  5. Thermostability characteristics of glucosephosphate and triosephosphate isomerase in erythrocytes from several species. Naidu, J.M., Turner, T.R., Mohrenweiser, H.W. Comp. Biochem. Physiol., B (1984) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities