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Gene Review

EZR  -  ezrin

Bos taurus

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Disease relevance of VIL2

  • METHODS: Following serological tests and identification of seropositive humans and animals for C. burnetii in two villages (VIL1 and VIL2), all seronegative individuals were followed up for one year on a monthly basis by trained physicians to detect possible seroconversion for Q fever [1].

High impact information on VIL2

  • We found that in MDCK epithelial cells, MBS accumulated at the tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling area, where moesin, a member of the ERM (ezrin, radixin, and moesin) family, was localized [2].

Other interactions of VIL2

  • Recombinant MBS interacted with the amino-terminal domains of moesin and ezrin [2].


  1. Active surveillance of Q fever in human and animal population of Cyprus. Loukaides, F., Hadjichristodoulou, C., Soteriades, E.S., Kolonia, V., Ioannidou, M.C., Psaroulaki, A., Tselentis, Y. BMC Infect. Dis. (2006) [Pubmed]
  2. Association of the myosin-binding subunit of myosin phosphatase and moesin: dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphatase. Fukata, Y., Kimura, K., Oshiro, N., Saya, H., Matsuura, Y., Kaibuchi, K. J. Cell Biol. (1998) [Pubmed]
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