Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

Serpinb1b - serine (or cysteine) peptidase inhibitor,...

Mus musculus

Synonyms: 6330533H24Rik, EIB, Leukocyte elastase inhibitor B, Serine protease inhibitor EIB, Serpin B1b, ...

Copple, B.L. et al., Benarafa, C. et al.

Benarafa, Cooley, Zeng, Bird, Remold-O'Donnell,

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Disease relevance of Serpinb1b

Inasmuch as HPC hypoxia occurred in the livers of MCT-treated animals, upregulation of the hypoxia-regulated cell-death factor, BNIP3 (Bcl2/adenovirus EIB 19kD-interacting protein 3), was examined [1].

High impact information on Serpinb1b

EIB is mainly expressed in brain, and EIC was only expressed as splicing variants unlikely to encode a functional serpin [2].

References

Modes of cell death in rat liver after monocrotaline exposure. Copple, B.L., Rondelli, C.M., Maddox, J.F., Hoglen, N.C., Ganey, P.E., Roth, R.A. Toxicol. Sci. (2004) [Pubmed]
Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1). Benarafa, C., Cooley, J., Zeng, W., Bird, P.I., Remold-O'Donnell, E. J. Biol. Chem. (2002) [Pubmed]

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