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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

PRTG  -  protogenin

Homo sapiens

Synonyms: FLJ25756, IGDCC5, Protein Shen-Dan, Protogenin
 
 
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Disease relevance of PRTG

  • Seventy-eight patients with tic douloureux who underwent 92 percutaneous radiofrequency trigeminal gangliolysis (PRTG) procedures were evaluated on average of 56 months postoperatively [1].
  • PRTG was associated wtih an 8% risk of complications, which included anesthesia dolorosa, corneal anesthesia with keratitis, and significant facial paresthesias [1].
  • Three different techniques may be used to perform percutaneous destruction of the ganglion: percutaneous radiofrequency trigeminal gangliolysis (PRTG), percutaneous balloon microcompression (PBM), and percutaneous retrogasserian glycerol rhizotomy (PRGR) [2].

References

  1. Comparison of percutaneous radiofrequency gangliolysis and microvascular decompression for the surgical management of tic douloureux. Burchiel, K.J., Steege, T.D., Howe, J.F., Loeser, J.D. Neurosurgery (1981) [Pubmed]
  2. Trigeminal neuralgia. Edlich, R.F., Winters, K.L., Britt, L., Long, W.B. Journal of long-term effects of medical implants. (2006) [Pubmed]
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